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血液系统恶性肿瘤中发热性中性粒细胞减少症的治疗与预防：一项批判性综述与更新

Treatment of febrile neutropenia and prophylaxis in hematologic malignancies: a critical review and update.

作者信息

Villafuerte-Gutierrez Paola, Villalon Lucia, Losa Juan E, Henriquez-Camacho Cesar

机构信息

Hospital Universitario Torrejón de Ardoz, Servicio de Hematología, Calle Mateo Inurria, 28850 Madrid, Spain.

Hospital Universitario Fundación Alcorcón, Servicio de Hematología, Calle Budapest 1, 28922 Madrid, Spain.

出版信息

Adv Hematol. 2014;2014:986938. doi: 10.1155/2014/986938. Epub 2014 Nov 27.

DOI:10.1155/2014/986938
PMID:25525436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4265549/
Abstract

Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival. This paper reviews the guidelines about febrile neutropenia in the setting of hematologic malignancies, providing an overview of the definition of fever and neutropenia, and categories of risk assessment, management of infections, and prophylaxis.

摘要

发热性中性粒细胞减少是血液系统恶性肿瘤患者和接受化疗患者最严重的并发症之一。及时识别感染并进行经验性抗生素治疗可延长生存期。本文综述了血液系统恶性肿瘤患者发热性中性粒细胞减少的相关指南，概述了发热和中性粒细胞减少的定义、风险评估类别、感染管理及预防措施。

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