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电化学疗法治疗肛门孔状癌1例罕见病例。

A rare case of anal porocarcinoma treated by electrochemotherapy.

作者信息

Borgognoni Lorenzo, Pescitelli Leonardo, Urso Carmelo, Brandani Paola, Sestini Serena, Chiarugi Cristina, Gelli Riccardo, Giannotti Vanni, Gerlini Gianni

出版信息

Future Oncol. 2014 Dec;10(15):2429-34. doi: 10.2217/fon.14.141.

Abstract

We report the case of an old woman with an eccrine porocarcinoma unusually localized in the perianal area treated by electrochemotherapy, a new technique, emerging as a very effective local treatment of different skin metastases and selected primary tumors. Electrochemotherapy was performed taking into account patient wishes and refusal of demolitive surgery. The electrochemotherapy treatment was well tolerated by the patient, it gave an excellent clinical response and a complete clinical regression with no sphincter dysfunction and signs of relapse observed during follow-up. The case is of particular interest for the exceptional localization of porocarcinoma for the first time treated by electrochemotherapy in this area. Electrochemotherapy could be considered as an alternative option for selected cases of cutaneous tumors.

摘要

我们报告了一例老年女性病例,其肛周区域出现罕见的小汗腺汗孔癌,采用电化学疗法进行治疗。电化学疗法是一种新兴的新技术,已成为治疗不同皮肤转移瘤和特定原发性肿瘤的非常有效的局部治疗方法。考虑到患者的意愿以及其拒绝进行破坏性手术,我们对其实施了电化学疗法。患者对电化学疗法耐受性良好,临床反应极佳,实现了完全临床缓解,随访期间未观察到括约肌功能障碍及复发迹象。该病例因其汗孔癌的特殊定位而格外引人关注,这是该区域首次采用电化学疗法进行治疗。对于某些特定的皮肤肿瘤病例,电化学疗法可被视为一种替代选择。

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