Quirk Matthew T, Pomykala Kelsey L, Suh Robert D
Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
Semin Thorac Cardiovasc Surg. 2014 Autumn;26(3):239-48. doi: 10.1053/j.semtcvs.2014.09.003. Epub 2014 Sep 21.
Percutaneous image-guided ablation is a technique for maintaining local control of metastatic lung lesions that may, in selected patients, confer a survival benefit over no treatment or systemic therapy alone. Although the currently accepted treatment for oligometastatic pulmonary disease is surgical resection, the existing body of literature, including the recent investigations reviewed within this article, supports a role for percutaneous ablation as an important and relatively safe therapeutic option for nonsurgical and in carefully selected surgical patients, conferring survival benefits competitive with surgical metastasectomy. Continued clinical investigations are needed to further understand the nuances of thermal technologies and applications to treat lung primary and secondary pulmonary malignancy, directly compare available therapeutic options and further define the role of percutaneous image-guided ablation in the treatment of pulmonary metastatic disease.
经皮影像引导下消融是一种用于维持转移性肺病变局部控制的技术，在部分特定患者中，与不治疗或仅采用全身治疗相比，可能具有生存获益。尽管目前公认的寡转移性肺疾病的治疗方法是手术切除，但现有文献（包括本文所回顾的近期研究）支持经皮消融作为非手术患者以及经过精心挑选的手术患者的一种重要且相对安全的治疗选择，其生存获益可与手术性转移灶切除术相媲美。需要持续进行临床研究，以进一步了解热技术及其在治疗肺部原发性和继发性恶性肿瘤中的应用细节，直接比较现有的治疗选择，并进一步明确经皮影像引导下消融在肺转移性疾病治疗中的作用。
