Arai Y, Konami T, Tomoyoshi T
Department of Urology, Shiga University of Medical Science.
Hinyokika Kiyo. 1989 Jun;35(6):1065-8.
We report a case of urachal carcinoma with elevated serum carcinoembryonic antigen (CEA) level in a 36-year-old man. En bloc resection was performed. The production of CEA was proved histologically. The level of serum CEA returned to the normal value after operation. Seventeen postoperative months the level of serum CEA was noted to be elevated again, and 2 months later symptoms appeared and tumor recurrence was revealed on computer tomographic scan. Radiotherapy and chemotherapy were done without any noticeable response. He died of tumor progression. In our case, serum CEA gave useful information as a tumor marker. It showed specificity for the tumor and helped evaluation of tumor resection as well as detection of tumor recurrence.
我们报告一例36岁男性脐尿管癌，其血清癌胚抗原（CEA）水平升高。进行了整块切除。组织学证实有CEA产生。术后血清CEA水平恢复正常。术后17个月，血清CEA水平再次升高，2个月后出现症状，计算机断层扫描显示肿瘤复发。进行了放疗和化疗，但无明显反应。患者死于肿瘤进展。在我们的病例中，血清CEA作为一种肿瘤标志物提供了有用信息。它显示出对肿瘤的特异性，有助于评估肿瘤切除情况以及检测肿瘤复发。
