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背根神经节脉冲射频治疗难治性椎体转移性疼痛:病例系列

Dorsal root ganglion pulsed radiofrequency for the management of intractable vertebral metastatic pain: a case series.

作者信息

Arai Young-Chang P, Nishihara Makoto, Yamamoto Yoshihiro, Arakawa Maki, Kondo Miki, Suzuki Chiharu, Kinoshita Akiko, Kambara Kazuyo, Ikemoto Tatsunori

机构信息

Multidisciplinary Pain Center, School of Medicine, Aichi Medical University, Aichi, Japan.

出版信息

Pain Med. 2015 May;16(5):1007-12. doi: 10.1111/pme.12629. Epub 2014 Dec 19.

Abstract

OBJECTIVE

Metastatic bone pain is characteristic of cancer pain and is a form of refractory cancer pain, as the pain includes not only nociceptive but also neuropathic pain. Although some drugs are effective in the management of painful bone metastases, pain while moving is one of the most refractory forms of pain. Although pulsed radiofrequency (RF) dramatically reduces neuropathic pain, chronic pain, and vertebral metastatic pain, the number of cases reported in these studies was very small (five or less).

DESIGN

Case report.

SETTING

Single pain center.

PATIENTS

Fifteen patients suffering from intractable vertebral metastatic pain.

INTERVENTIONS

Dorsal root ganglion (DRG) pulsed RF.

OUTCOME MEASURES

A numerical rating scale (NRS) of pain at rest and while moving.

RESULTS

Almost all patients experienced sound pain relief after the pulsed RF treatment. There were no severe side effects reported.

CONCLUSION

DRG pulsed RF procedure provided sound pain relief for patients with intractable vertebral metastatic pain. Metastatic bone pain is characteristic of cancer pain and is a form of refractory cancer pain, as the pain includes not only nociceptive but also neuropathic pain. Although some drugs are effective in the management of painful bone metastases, pain while moving is one of the most refractory forms of pain. DRG pulsed RF procedure provided sound pain relief for patients with intractable vertebral metastatic pain.

摘要

目的

转移性骨痛是癌痛的特征之一,是一种难治性癌痛形式,因为这种疼痛不仅包括伤害感受性疼痛,还包括神经性疼痛。尽管一些药物在治疗疼痛性骨转移方面有效,但活动时的疼痛是最难治的疼痛形式之一。尽管脉冲射频(RF)能显著减轻神经性疼痛、慢性疼痛和椎体转移性疼痛,但这些研究中报道的病例数量非常少(5例或更少)。

设计

病例报告。

地点

单一疼痛中心。

患者

15例患有顽固性椎体转移性疼痛的患者。

干预措施

背根神经节(DRG)脉冲射频。

观察指标

静息和活动时疼痛的数字评分量表(NRS)。

结果

几乎所有患者在脉冲射频治疗后疼痛都得到了明显缓解。未报告严重副作用。

结论

DRG脉冲射频手术为患有顽固性椎体转移性疼痛的患者提供了明显的疼痛缓解。转移性骨痛是癌痛的特征之一,是一种难治性癌痛形式,因为这种疼痛不仅包括伤害感受性疼痛,还包括神经性疼痛。尽管一些药物在治疗疼痛性骨转移方面有效,但活动时的疼痛是最难治的疼痛形式之一。DRG脉冲射频手术为患有顽固性椎体转移性疼痛的患者提供了明显的疼痛缓解。

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