Curto-Barredo Laia, Vicente Asunción, Rovira Carlota, García-Diez Eloy, Pujol Ramón M, González-Enseñat Maria Antonia
Department of Dermatology, Hospital Sant Joan de Deu, Barcelona, Spain.
Department of Pathology, Hospital Sant Joan de Deu, Barcelona, Spain.
Pediatr Dermatol. 2015 Jul-Aug;32(4):536-8. doi: 10.1111/pde.12487. Epub 2014 Dec 22.
We report the fifth case of epidermal choristoma of the oral cavity in a Caucasian newborn with a congenital melanotic macule on the dorsum of the tongue. Epidermal choristoma is an exceedingly rare and benign condition probably caused by a developmental abnormality. It is identified according to the presence of normal skin in an abnormal location. Histologically it is identified according to areas of stratified epithelium and hyperpigmentation of the basal layer along with cutaneous adnexal structures (hair follicles, sebaceous or sweat glands). The clinical presentation is variable, but most of the cases described presented with a congenital lingual pigmented macule. These lesions should be included within the differential diagnosis of congenital lingual macules and distinguished from other entities such as congenital lingual melanotic macules and melanocytic lesions. Surgical excision is the treatment of choice. Epidermal choristoma is a benign condition that probably is underdiagnosed because it is a new and rare entity, and dermatologists should be aware of it.
我们报告了第五例口腔表皮迷离瘤病例，该病例发生于一名患有先天性舌背黑素斑的高加索新生儿。表皮迷离瘤是一种极其罕见的良性疾病，可能由发育异常引起。它是根据异常部位出现正常皮肤来确定的。组织学上，它是根据分层上皮区域、基底层色素沉着以及皮肤附属结构（毛囊、皮脂腺或汗腺）来确定的。临床表现各不相同，但大多数报道的病例都表现为先天性舌部色素斑。这些病变应列入先天性舌部斑疹的鉴别诊断范围，并与其他实体如先天性舌部黑素斑和黑素细胞病变相区分。手术切除是首选治疗方法。表皮迷离瘤是一种良性疾病，可能由于它是一种新的罕见实体而未得到充分诊断，皮肤科医生应该对此有所了解。
