1,8-萘啶衍生物对血小板聚集的抑制作用研究。
Study of inhibition of platelet aggregation of 1,8-naphthyridine derivatives.
作者信息
Ferrarini P, Mori C, Criscuoli M
机构信息
Istituto di Chimica Farmaceutica e Tossicologica Dell'Università di Pisa.
出版信息
Farmaco. 1989 Jun;44(6):579-84.
PMID:2553036
Abstract
The antiplatelet activity of some 1,8-naphthyridine derivatives was studied. The compounds displayed different abilities in blocking the effects of ADP, collagen and arachidonic acid. Four of them showed an in vitro remarkable activity similar to that of dipyridamole and papaverine.
摘要
研究了一些1,8-萘啶衍生物的抗血小板活性。这些化合物在阻断ADP、胶原蛋白和花生四烯酸的作用方面表现出不同的能力。其中四种在体外显示出与双嘧达莫和罂粟碱相似的显著活性。
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