• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Patient-Specific Pluripotent Stem Cells in Doxorubicin Cardiotoxicity: A New Window Into Personalized Medicine.

作者信息

Bernstein Daniel, Burridge Paul

机构信息

Departments of Pediatrics and Medicine, Stanford Cardiovascular Institute, Stanford University.

出版信息

Prog Pediatr Cardiol. 2014 Dec 1;37(1-2):23-27. doi: 10.1016/j.ppedcard.2014.10.006.

DOI:10.1016/j.ppedcard.2014.10.006
PMID:25530693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4267060/
Abstract
摘要

相似文献

1
Patient-Specific Pluripotent Stem Cells in Doxorubicin Cardiotoxicity: A New Window Into Personalized Medicine.多柔比星心脏毒性中的患者特异性多能干细胞:个性化医疗的新窗口。
Prog Pediatr Cardiol. 2014 Dec 1;37(1-2):23-27. doi: 10.1016/j.ppedcard.2014.10.006.
2
MicroRNA-mediated maturation of human pluripotent stem cell-derived cardiomyocytes: Towards a better model for cardiotoxicity?微小RNA介导的人多能干细胞衍生心肌细胞的成熟:迈向更好的心脏毒性模型?
Food Chem Toxicol. 2016 Dec;98(Pt A):17-24. doi: 10.1016/j.fct.2016.05.025. Epub 2016 Jun 3.
3
Identification of novel biomarkers for doxorubicin-induced toxicity in human cardiomyocytes derived from pluripotent stem cells.鉴定多能干细胞来源的人心肌细胞中阿霉素诱导毒性的新型生物标志物。
Toxicology. 2015 Feb 3;328:102-11. doi: 10.1016/j.tox.2014.12.018. Epub 2014 Dec 18.
4
HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity.曲妥珠单抗靶向脂质体多柔比星显示出增强的抗肿瘤作用而无相关心脏毒性。
Toxicol Appl Pharmacol. 2012 Jul 1;262(1):1-10. doi: 10.1016/j.taap.2012.04.008. Epub 2012 Apr 21.
5
Monitoring Trastuzumab Resistance and Cardiotoxicity: A Tale of Personalized Medicine.监测曲妥珠单抗耐药性和心脏毒性:个体化医学的故事。
Adv Clin Chem. 2015;70:95-130. doi: 10.1016/bs.acc.2015.03.006. Epub 2015 Apr 27.
6
Human pluripotent stem cell-derived cardiomyocyte based models for cardiotoxicity and drug discovery.用于心脏毒性研究和药物发现的人多能干细胞衍生心肌细胞模型
Expert Opin Drug Saf. 2016 Nov;15(11):1455-1458. doi: 10.1080/14740338.2016.1223624. Epub 2016 Sep 9.
7
How induced pluripotent stem cells are redefining personalized medicine.诱导多能干细胞如何重新定义个性化医疗。
Gene. 2013 May 10;520(1):1-6. doi: 10.1016/j.gene.2013.02.037. Epub 2013 Mar 5.
8
Protective effect of 23-hydroxybetulinic acid on doxorubicin-induced cardiotoxicity: a correlation with the inhibition of carbonyl reductase-mediated metabolism.23-羟基桦木酸对阿霉素诱导的心脏毒性的保护作用:与抑制羰基还原酶介导的代谢的相关性
Br J Pharmacol. 2015 Dec;172(23):5690-703. doi: 10.1111/bph.12995. Epub 2015 Jan 12.
9
Evaluation of nefazodone-induced cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytes.奈法唑酮在人诱导多能干细胞衍生心肌细胞中诱导心脏毒性的评估。
Toxicol Appl Pharmacol. 2016 Apr 1;296:42-53. doi: 10.1016/j.taap.2016.01.015. Epub 2016 Jan 25.
10
[In vitro generation of blood red cells from stem cells: a sketch of the future].[从干细胞体外生成红细胞:未来展望]
Biol Aujourdhui. 2016;210(1):9-17. doi: 10.1051/jbio/2016008. Epub 2016 Jun 10.

引用本文的文献

1
Ferruginol Restores SIRT1-PGC-1α-Mediated Mitochondrial Biogenesis and Fatty Acid Oxidation for the Treatment of DOX-Induced Cardiotoxicity.铁杉醇通过恢复SIRT1-PGC-1α介导的线粒体生物合成和脂肪酸氧化来治疗阿霉素诱导的心脏毒性。
Front Pharmacol. 2021 Nov 24;12:773834. doi: 10.3389/fphar.2021.773834. eCollection 2021.
2
Genome-wide CRISPR/Cas9 screening in human iPS derived cardiomyocytes uncovers novel mediators of doxorubicin cardiotoxicity.全基因组 CRISPR/Cas9 筛选在人类诱导多能干细胞衍生的心肌细胞中揭示了多柔比星心脏毒性的新介质。
Sci Rep. 2021 Jul 6;11(1):13866. doi: 10.1038/s41598-021-92988-1.
3
Human In Vitro Models for Assessing the Genomic Basis of Chemotherapy-Induced Cardiovascular Toxicity.用于评估化疗诱导的心血管毒性的基因组基础的人体体外模型。
J Cardiovasc Transl Res. 2020 Jun;13(3):377-389. doi: 10.1007/s12265-020-09962-x. Epub 2020 Feb 20.
4
Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.人诱导多能干细胞衍生的心肌细胞重现了乳腺癌患者对阿霉素诱导的心脏毒性的易感性。
Nat Med. 2016 May;22(5):547-56. doi: 10.1038/nm.4087. Epub 2016 Apr 18.

本文引用的文献

1
hiPSC Modeling of Inherited Cardiomyopathies.遗传性心肌病的人诱导多能干细胞建模
Curr Treat Options Cardiovasc Med. 2014 Jul;16(7):320. doi: 10.1007/s11936-014-0320-7.
2
Cardiac stem cell biology: glimpse of the past, present, and future.心脏干细胞生物学:过去、现在和未来的一瞥。
Circ Res. 2014 Jan 3;114(1):21-7. doi: 10.1161/CIRCRESAHA.113.302895.
3
Genetic susceptibility to anthracycline-related congestive heart failure in survivors of haematopoietic cell transplantation.造血细胞移植幸存者中蒽环类药物相关性充血性心力衰竭的遗传易感性。
Br J Haematol. 2013 Oct;163(2):205-13. doi: 10.1111/bjh.12516. Epub 2013 Aug 8.
4
Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia.铁沉积病基因突变对蒽环类药物治疗的儿童高危白血病幸存者心脏状况的影响。
Cancer. 2013 Oct 1;119(19):3555-62. doi: 10.1002/cncr.28256. Epub 2013 Jul 16.
5
Modeling human disease with pluripotent stem cells: from genome association to function.利用多能干细胞进行人类疾病建模:从基因组关联到功能。
Cell Stem Cell. 2013 Jun 6;12(6):656-68. doi: 10.1016/j.stem.2013.05.016.
6
Association of anthracycline-related cardiac histological lesions with NADPH oxidase functional polymorphisms.蒽环类相关心脏组织学病变与 NADPH 氧化酶功能多态性的关联。
Oncologist. 2013;18(4):446-53. doi: 10.1634/theoncologist.2012-0239. Epub 2013 Apr 10.
7
Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.验证 SLC28A3 和 UGT1A6 中的变体是否可作为预测儿童蒽环类药物诱导性心脏毒性的遗传标志物。
Pediatr Blood Cancer. 2013 Aug;60(8):1375-81. doi: 10.1002/pbc.24505. Epub 2013 Feb 25.
8
Doxorubicin induces senescence and impairs function of human cardiac progenitor cells.多柔比星诱导人心脏祖细胞衰老并损害其功能。
Basic Res Cardiol. 2013 Mar;108(2):334. doi: 10.1007/s00395-013-0334-4. Epub 2013 Feb 15.
9
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells.异常的钙处理特性是家族性肥厚型心肌病患者特异性诱导多能干细胞病理的基础。
Cell Stem Cell. 2013 Jan 3;12(1):101-13. doi: 10.1016/j.stem.2012.10.010.
10
RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cells.RARγ 对于维甲酸诱导的胚胎干细胞染色质重塑和转录激活是必不可少的。
J Cell Sci. 2013 Feb 15;126(Pt 4):999-1008. doi: 10.1242/jcs.119701. Epub 2012 Dec 21.