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[猫逆转录病毒与人类逆转录病毒:比较要素]

[Cat retroviruses and human retroviruses: elements of comparison].

作者信息

Pilet C, Barre-Sinoussi F, Quintin-Colonna F, Boulouis H J, Pedersen N C, Elder J H

出版信息

Bull Acad Natl Med. 1989 May;173(5):617-32; discussion 632-3.

PMID:2553219
Abstract

Following emotional head-lines of certain articles in the press, making believe that the cat could be susceptible to the AIDS virus, the authors present elements of comparison between principal feline retroviruses (the feline leucosis virus and the feline immunodeficiency virus) and the two human immunodeficiency viruses (HIV). The feline leucosis virus in differentiated from the human and the feline immunodeficiency viruses by its virological, pathological and epidemiological characteristics. Being close to the AIDS virus in the taxonomy of retroviruses, the feline immunodeficiency virus (FIV) presents a number of similarities with the HIV. Therefore, the FIV could give rise to interests in its use as a model in the study of AIDS. Whatever the factors of resemblances may be, there are no elements of present knowledge in favor of an inter-species contamination (cat-man); on the contrary, these viruses demonstrate a marked species specificity.

摘要

根据媒体上某些文章耸人听闻的标题,人们误以为猫可能易感染艾滋病病毒,作者介绍了主要猫逆转录病毒(猫白血病病毒和猫免疫缺陷病毒)与两种人类免疫缺陷病毒(HIV)之间的比较内容。猫白血病病毒在病毒学、病理学和流行病学特征方面与人类及猫免疫缺陷病毒有所不同。猫免疫缺陷病毒(FIV)在逆转录病毒分类学上与艾滋病病毒相近,与HIV有许多相似之处。因此,FIV可能会引起人们将其用作艾滋病研究模型的兴趣。无论相似因素为何,目前尚无已知证据支持跨物种感染(猫传人);相反,这些病毒表现出明显的物种特异性。

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