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血管性勃起功能障碍的血管内治疗

Endovascular treatment of vasculogenic erectile dysfunction.

作者信息

Kim Edward D, Owen Ryan C, White Gregory S, Elkelany Osama O, Rahnema Cyrus D

出版信息

Asian J Androl. 2015 Jan-Feb;17(1):40-3. doi: 10.4103/1008-682x.143752.

Abstract

The treatment of erectile dysfunction (ED) has been a fascination involving multiple medical specialities over the past century with urologic, cardiac and surgical experts all contributing knowledge toward this multifactorial disease. With the well-described association between ED and cardiovascular disease, angiography has been utilized to identify vasculogenic impotence. Given the success of endovascular drug-eluting stent (DES) placement for the treatment of coronary artery disease, there has been interest in using this same technology for the treatment of vasculogenic ED. For men with inflow stenosis, DES placement to bypass arterial lesions has recently been reported with a high technical success rate. Comparatively, endovascular embolization as an approach to correct veno-occlusive dysfunction has produced astonishing procedural success rates as well. However, after a thorough literature review, arterial intervention is only recommended for younger patients with isolated vascular injuries, typically from previous traumatic experiences. Short-term functional outcomes are less than optimal with long-term results yet to be determined. In conclusion, the hope for a minimally invasive approach to ED persists but additional investigation is required prior to universal endorsement.

摘要

在过去的一个世纪里,勃起功能障碍(ED)的治疗一直吸引着多个医学专业领域,泌尿外科、心脏科和外科专家都为这种多因素疾病贡献了知识。鉴于ED与心血管疾病之间已得到充分描述的关联,血管造影已被用于识别血管性阳痿。鉴于血管内药物洗脱支架(DES)置入术在治疗冠状动脉疾病方面取得的成功,人们对将同样的技术用于治疗血管性ED产生了兴趣。对于存在流入道狭窄的男性,最近有报道称,通过DES置入术绕过动脉病变,技术成功率很高。相比之下,血管内栓塞作为一种纠正静脉闭塞功能障碍的方法,也取得了惊人的手术成功率。然而,在全面的文献综述之后,动脉干预仅推荐用于患有孤立性血管损伤的年轻患者,这些损伤通常源于既往的创伤经历。短期功能结果并不理想,长期结果还有待确定。总之,对ED进行微创治疗的希望依然存在,但在得到普遍认可之前还需要进一步研究。

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