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勃起功能障碍:通往心脏的一扇窗。

Erectile dysfunction: a window to the heart.

作者信息

Androshchuk Vitaliy, Pugh Neil, Wood Andrew, Ossei-Gerning Nick

机构信息

University Hospital of Wales, Cardiff, UK.

出版信息

BMJ Case Rep. 2015 Apr 28;2015:bcr2015210124. doi: 10.1136/bcr-2015-210124.

DOI:10.1136/bcr-2015-210124
PMID:25920740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4422912/
Abstract

Erectile dysfunction (ED) is an early marker of coronary artery disease (CAD) and often manifests before the development of symptomatic CAD. In this case report, we present a 60-year-old man with ED, who demonstrated limited response to the standard management strategies and was subsequently treated with percutaneous pelvic intervention (PPI) of the internal pudendal artery. While on the table for PPI, the patient described a classical history of angina, on which basis he underwent coronary angiography and was found to have narrow proximal left anterior descending stenosis. Coronary artery stent placement was then performed using standard techniques. PPI of pudendal artery stenoses with stents is feasible and can improve cavernosal blood flow and venous leakage as well as erectile function.

摘要

勃起功能障碍(ED)是冠状动脉疾病(CAD)的早期标志物,且常在有症状的CAD发生之前就出现。在本病例报告中,我们介绍了一名60岁患有ED的男性,他对标准治疗策略反应有限,随后接受了阴部内动脉的经皮盆腔介入治疗(PPI)。在进行PPI手术时,患者描述了典型的心绞痛病史,基于此他接受了冠状动脉造影,结果发现左前降支近端狭窄。然后使用标准技术进行了冠状动脉支架置入术。用支架对阴部动脉狭窄进行PPI是可行的,并且可以改善海绵体血流和静脉漏以及勃起功能。

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本文引用的文献

1
Treatment Strategy for Non-Responders to PDE5 Inhibitors.对 PDE5 抑制剂无反应者的治疗策略。
World J Mens Health. 2013 Apr;31(1):31-5. doi: 10.5534/wjmh.2013.31.1.31. Epub 2013 Apr 23.
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Erectile dysfunction in the cardiovascular patient.心血管病患者的勃起功能障碍。
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Prediction of cardiovascular events and all-cause mortality with erectile dysfunction: a systematic review and meta-analysis of cohort studies.勃起功能障碍对心血管事件和全因死亡率的预测:队列研究的系统评价和荟萃分析
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Zotarolimus-eluting peripheral stents for the treatment of erectile dysfunction in subjects with suboptimal response to phosphodiesterase-5 inhibitors.西罗莫司涂层外周支架治疗对磷酸二酯酶-5 抑制剂反应不佳的患者的勃起功能障碍。
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Erectile dysfunction and coronary artery disease prediction: evidence-based guidance and consensus.勃起功能障碍与冠状动脉疾病预测:循证指导与共识。
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Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation.男性性功能障碍指南:勃起功能障碍和早泄。
Eur Urol. 2010 May;57(5):804-14. doi: 10.1016/j.eururo.2010.02.020. Epub 2010 Feb 20.
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Cavernous artery intima-media thickness: a new parameter in the diagnosis of vascular erectile dysfunction.海绵体动脉内膜中层厚度:血管性勃起功能障碍诊断的新参数。
J Sex Med. 2009 Apr;6(4):1117-1126. doi: 10.1111/j.1743-6109.2008.01112.x. Epub 2008 Dec 5.
8
British Society for Sexual Medicine guidelines on the management of erectile dysfunction.英国性医学学会勃起功能障碍管理指南。
J Sex Med. 2008 Aug;5(8):1841-65. doi: 10.1111/j.1743-6109.2008.00773.x. Epub 2008 Feb 21.
9
Association between erectile dysfunction and coronary artery disease: Matching the right target with the right test in the right patient.勃起功能障碍与冠状动脉疾病之间的关联:在合适的患者中,将正确的检测与正确的目标相匹配。
Eur Urol. 2006 Oct;50(4):721-31. doi: 10.1016/j.eururo.2006.07.015. Epub 2006 Jul 28.
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Prevalence of asymptomatic coronary artery disease in men with vasculogenic erectile dysfunction: a prospective angiographic study.血管源性勃起功能障碍男性无症状冠状动脉疾病的患病率:一项前瞻性血管造影研究。
Eur Urol. 2005 Dec;48(6):996-1002; discussion 1002-3. doi: 10.1016/j.eururo.2005.08.002. Epub 2005 Aug 24.