Thomsen H S, Lund J O, Munck O, Andersen K W
Department of Clinical Physiology and Nuclear Medicine, Copenhagen County Hospital, Herlev.
Dan Med Bull. 1989 Oct;36(5):481-3.
From 1977 to 1987, 7,604 out of a total of 20,483 Danish breast cancer patients had a bone scintigraphy in order to exclude or localise osseous metastases. The scintigrams were performed and interpreted at 14 local hospitals. In 1979, standardised guidelines for interpretation were agreed upon. Until 1983, the scintigrams were described centrally, based on the local reports. From 1979, the frequency of positive bone scintigrams suggesting bone metastases stabilised at about 5% of the patients compared with 12 and 20% in 1977-78. The local take-over of description did not change the frequency. The frequency was also stable from 1979 when evaluated in age groups. With increasing age the frequency of positive scintigrams increased. The frequency of positive scintigrams was significantly lower in patients entering a protocol than in those not entering a protocol. The conclusion is that on a nation-wide basis it is possible to establish a stable, uniform interpretation of bone scintigrams after a two-year introduction period.
1977年至1987年期间，丹麦20483名乳腺癌患者中有7604人接受了骨闪烁扫描，以排除或定位骨转移。这些闪烁扫描由14家当地医院进行并解读。1979年，就解读的标准化指南达成了一致。1983年之前，闪烁扫描结果是根据当地报告集中描述的。从1979年起，提示骨转移的阳性骨闪烁扫描频率稳定在约5%的患者，而1977 - 1978年为12%和20%。描述工作由当地负责并未改变这一频率。按年龄组评估时，该频率自1979年起也保持稳定。随着年龄增长，阳性闪烁扫描的频率增加。进入一项方案的患者中阳性闪烁扫描的频率显著低于未进入该方案的患者。结论是，在全国范围内，经过两年的引入期后，有可能对骨闪烁扫描结果建立稳定、统一的解读。
