Ichinose Y, Hara N, Ohta M, Motohiro A, Maeda T, Nobe T, Yagawa K
Department of Chest Surgery, National Kyushu Cancer Center, Fukuoka, Japan.
Chest. 1989 Nov;96(5):1104-9. doi: 10.1378/chest.96.5.1104.
The purpose of the present study was to determine whether all patients with non-small cell lung cancer, clinically defined as stage 1 or 2, should have examinations to determine the presence of distant metastatic (M1) disease. The survival rates of patients who underwent the examinations and those who did not were compared. In all groups, the examinations had in no way positively affected survival. The 33 patients in whom distant recurrence had occurred within 12 months of curative operation, were then evaluated to establish the relationship between the recurrent site and the preoperative examination: negative scans on the examination failed to predict the low incidence of early distant recurrence. Those data suggest that the routine use of radionuclide or CT scans is of no benefit to asymptomatic patients with local, early disease.
本研究的目的是确定所有临床定义为1期或2期的非小细胞肺癌患者是否都应进行检查以确定是否存在远处转移(M1)疾病。对接受检查和未接受检查的患者的生存率进行了比较。在所有组中,检查均未对生存率产生积极影响。然后对33例在根治性手术后12个月内发生远处复发的患者进行评估,以确定复发部位与术前检查之间的关系:检查时扫描结果为阴性未能预测早期远处复发的低发生率。这些数据表明,对于无症状的局部早期疾病患者,常规使用放射性核素或CT扫描并无益处。