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[影响胰头癌胰十二指肠切除术后长期预后的因素]

[Factors influencing long-term prognosis after pancreatoduodenectomy in cancer of the pancreas head].

作者信息

Liang X M

出版信息

Zhonghua Wai Ke Za Zhi. 1989 Apr;27(4):211-4, 253.

PMID:2553357
Abstract

Sixty-four cases of pancreatoduodenectomy were performed for ductal adenocarcinoma of the head of pancreas. According to the size of primary tumor, the cases were divided into 3 groups: less than 2 cm, 2.1 to 4.0 cm, and more than 4 cm. The corresponding one-year survival was 66.7%, 33.7%, and 25.0% (P less than 0.05), respectively. The one-year survival of cases with tumor confined to pancreas or only involving intrapancreatic common bile duct or duodenal wall in the ampullary region (100%) was higher than that of cases with microscopic and macroscopic local infiltration (33.3%, 54.5%) and that of cases with large or middle extrapancreatic vessels involved (11.1%) (P less than 0.001). The rate of lymph node metastases of all cases was 69%. The one-year survival of cases with primary lymph node metastases was lower than that of cases without it (32.4% v. 62.5%, P less than 0.05). Based on the above mentioned result, a new staging method is suggested.

摘要

对64例胰腺导管腺癌患者实施了胰十二指肠切除术。根据原发肿瘤大小,将病例分为3组:小于2厘米、2.1至4.0厘米和大于4厘米。相应的1年生存率分别为66.7%、33.7%和25.0%(P<0.05)。肿瘤局限于胰腺或仅累及壶腹区域胰内胆总管或十二指肠壁的病例(100%)的1年生存率高于有微观和宏观局部浸润的病例(33.3%、54.5%)以及有大或中等胰外血管受累的病例(11.1%)(P<0.001)。所有病例的淋巴结转移率为69%。有原发性淋巴结转移的病例的1年生存率低于无原发性淋巴结转移的病例(32.4%对62.5%,P<0.05)。基于上述结果,建议采用一种新的分期方法。

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