2014 年肺癌：优化肺癌治疗方法。
Lung cancer in 2014: optimizing lung cancer treatment approaches.
机构信息
Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Campus Can Ruti, Carretera Canyet s/n, 08916 Badalona, Barcelona, Spain.
Fundación Molecular Oncology Research (MORe), Quirón Dexeus University Hospital, Sabino Arana 5-19, 08028 Barcelona, Spain.
出版信息
Nat Rev Clin Oncol. 2015 Feb;12(2):75-6. doi: 10.1038/nrclinonc.2014.225. Epub 2014 Dec 23.
In 2014, developments in our understanding of escape signalling circuits implicated in resistance to targeted agents in patients with lung cancer have led to improvements in tackling such resistance. The potential role for PET in the management of erlotinib therapy, novel combination therapies and pharmacogenomic-driven individualization of platinum-based chemotherapy represent other key advances.
2014 年，我们对肺癌患者中靶向药物耐药相关逃逸信号通路的认识有了新的进展，这也推动了耐药问题的解决。正电子发射断层扫描（PET）在厄洛替尼治疗管理、新型联合治疗以及基于药物基因组学的铂类化疗个体化方面的潜在作用是其他关键进展。
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