超声引导下多药分层介入治疗剖宫产瘢痕妊娠。
Ultrasonography-guided multidrug stratification interventional therapy for cesarean scar pregnancy.
机构信息
Department of Ultrasonography, The Fourth Hospital of Harbin Medical University, Yiyuan Str 37, Harbin, 150001, Heilongjiang, People's Republic of China.
出版信息
Arch Gynecol Obstet. 2015 Jul;292(1):143-8. doi: 10.1007/s00404-014-3602-0. Epub 2014 Dec 23.
PURPOSE
To explore the clinical value of ultrasonography-guided multidrug stratification interventional therapy for cesarean scar pregnancy (CSP).
METHODS
Aspiration of gestational sac fluid, injection of methotrexate in the sac, injection of homeostatic agent and pituitrin in the uterine muscle layer, and injection of triple anti-inflammatory drugs around the uterus in 12 patients with CSP. The lesion volume, serum β-hCG level, and blood flow were observed.
RESULTS
The mean β-hCG level continued to decrease posttreatment, and the greatest reduction occurred in week 1. The mean number of days needed for serum β-hCG values to decrease to normal level was 39.1 ± 10.1 days. Mass volumes reduced and the mean number of days for the masses to disappear was 24.6 ± 14.1 days. The blood flow around the lesions continued to decrease.
CONCLUSIONS
Ultrasonography-guided multidrug interventional therapy for CSP is a new, safe, effective, minimally invasive method.
目的
探讨超声引导下多药物分层介入治疗剖宫产瘢痕妊娠（CSP）的临床价值。
方法
对 12 例 CSP 患者行孕囊内抽吸、囊内注射甲氨蝶呤、子宫肌层注射平衡液及垂体后叶素、子宫周围注射三联抗炎药物。观察病灶体积、血清β-hCG 水平及血流情况。
结果
治疗后血清β-hCG 水平持续下降，第 1 周下降最明显。血清β-hCG 值降至正常所需的平均天数为 39.1±10.1 天。肿块体积缩小，肿块消失的平均天数为 24.6±14.1 天。病灶周围血流持续减少。
结论
超声引导下多药物介入治疗 CSP 是一种新的、安全、有效、微创的方法。
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