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Opioid receptor affinities of the blood-derived tetrapeptides hemorphin and cytochrophin.

作者信息

Liebmann C, Schrader U, Brantl V

机构信息

Department of Biology, Friedrich-Schiller-University Jena, G.D.R.

出版信息

Eur J Pharmacol. 1989 Aug 3;166(3):523-6. doi: 10.1016/0014-2999(89)90368-3.

Abstract

Hemorphin-4 and cytochrophin-4 displayed affinities for mu- and delta-opioid receptors that were in the same range as those observed for the structurally related beta-casomorphins. However, they showed markedly higher affinities at kappa-opioid binding sites when compared to the beta-casomorphins. These blood-derived peptides could be involved in blood pressure regulation.

摘要

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