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[大鼠冷适应过程中突触前装置功能的定量评估]

[Quantitative evaluation of the function of the presynaptic apparatus of the rat in cold adaptation].

作者信息

Shtan'ko S A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1989 Jun;75(6):857-62.

PMID:2553501
Abstract

Binomial parameters of transmitter secretion were calculated on the basis of synaptic potential analysis for the diaphragm and extensor digitorum longus muscles of the control and cold-adapted rats. The quantum content, amplitude of EPPs and the amount of available transmitter increased in these muscles of cold-adapted rats. This may be due to the influences of neurohumoral factors on the presynapse or, on the other hand, to changes in metabolism of the nerve terminal. Differences in presynaptic characteristics of the muscles between the control and the cold-adapted rats indicate the high reliability of the neuro-muscular junction functioning during slow rhythmic stimulation in cold ambient condition and the identical processes in the nerve terminal in the two groups of muscles.

摘要

基于对对照大鼠和冷适应大鼠膈肌及趾长伸肌的突触电位分析,计算了递质分泌的二项式参数。冷适应大鼠这些肌肉中的量子含量、终板电位幅度和可用递质数量均增加。这可能是由于神经体液因素对突触前的影响,或者另一方面是由于神经末梢代谢的变化。对照大鼠和冷适应大鼠肌肉突触前特征的差异表明,在寒冷环境条件下缓慢节律性刺激期间神经肌肉接头功能的高可靠性,以及两组肌肉神经末梢中的相同过程。

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