von Glass W, Pesch H J, Braun R, Krause J
Klinik für Hals-, Nasen- und Ohrenkranke, Universität Erlangen-Nürnberg.
HNO. 1989 Oct;37(10):426-31.
In literature opinion is divided, whether for treatment of pleomorphic adenoma in the parotid gland partial parotidectomy is adequate or complete parotidectomy is necessary. In a retrospective analysis of 123 complete parotidectomies in pleomorphic adenomas the macroscopic tumor extension was compared with the microscopic findings. Additionally 35 pleomorphic adenomas were examined in histological serial sections. The retrospective analysis showed in 6%, the serial sections in 11% microscopic tumor in the macroscopic tumorfree inner lobe. A clinical follow-up examination of 85 patients operated by complete parotidectomy because pleomorphic adenoma resulted in a relapse-quota of 3.5%. The function of the facial nerve was in most cases normal, in 8.2% a weakness of the mandibular branch was found. These results indicate that the risk to leave tumor can be reduced evidently by a complete parotidectomy.
在文献中，对于腮腺多形性腺瘤的治疗，部分腮腺切除术是否足够，还是需要进行全腮腺切除术，存在不同观点。在对123例多形性腺瘤全腮腺切除术的回顾性分析中，将宏观肿瘤范围与微观检查结果进行了比较。此外，对35例多形性腺瘤进行了组织学连续切片检查。回顾性分析显示，6%的病例中，连续切片检查发现11%的病例在宏观上无肿瘤的内叶存在微观肿瘤。对85例因多形性腺瘤接受全腮腺切除术的患者进行临床随访检查，复发率为3.5%。面神经功能在大多数情况下正常，8.2%的患者发现下颌支无力。这些结果表明，通过全腮腺切除术可以明显降低残留肿瘤的风险。
