Uaratanawong Rawipan, Kootiratrakarn Tanawatt, Sudtikoonaseth Poonnawis, Issara Atjima, Kattipathanapong Pinnaree
J Med Assoc Thai. 2014 Sep;97(9):993-7.
Congenital self-healing reticulohistiocytosis, also known as Hashimoto-Pritzker disease, is a single system Langerhans cell histiocytosis that typically presents in healthy newborns and spontaneously regresses. In the present report, we described a 2-month-old Thai female newborn with multiple hypopigmented flat-topped papules without any internal organ involvement including normal blood cell count, urinary examination, liver and renal functions, bone scan, chest X-ray, abdominal ultrasound, and bone marrow biopsy. The histopathology revealed typical findings of Langerhans cell histiocytosis, which was confirmed by the immunohistochemical staining CDla and S100. Our patient's lesions had spontaneously regressed within afew months, and no new lesion recurred afterfour months follow-up.
先天性自愈性网状组织细胞增生症，也称为桥本-普利茨克病，是一种单系统朗格汉斯细胞组织细胞增生症，通常发生于健康新生儿，且可自发消退。在本报告中，我们描述了一名2个月大的泰国女新生儿，其有多个色素减退的平顶丘疹，无任何内脏器官受累，包括血常规、尿液检查、肝肾功能、骨扫描、胸部X线、腹部超声和骨髓活检均正常。组织病理学显示朗格汉斯细胞组织细胞增生症的典型表现，免疫组化染色CD1a和S100证实了这一点。我们患者的皮损在几个月内自发消退，随访4个月后无新皮损复发。
