Berdina O N, Madaeva I M, Dolgikh V V
Vopr Kurortol Fizioter Lech Fiz Kult. 2014 Sep-Oct(5):21-5.
The present study was designed to estimate the effectiveness of non-invasive auxiliary lung ventilation under continuous positive airway pressure (CPAP therapy) and phototherapy applied for the treatment of adolescents presenting with essential arterial hypertension and obstructive sleep apnea/hypopnea. It was shown that CPAP therapy decreased the level of arterial pressure (AP) either to normal or to high normal values in accordance with the patients' gender and age. It was confirmed that phototherapy produced beneficial effect on the system of circadian rhythms in the patients with essential hypertension. These findings give reason to recommend the combined application of the above methods for the treatment of adolescents with essential hypertension and obstructive sleep apnea/hypopnea. The proposed treatment makes it possible to decrease arterial pressure due to the correction of obstructive breathing disorders in sleep and to normalize the circadian rhythm system in the adolescents suffering from essential hypertension and obstructive sleep apnea/hypopnea. The clinical application of this method would permit to reduce morbidity, the incidence of disability, and mortality from complications developing in adulthood.
本研究旨在评估无创辅助通气在持续气道正压通气（CPAP治疗）及光疗应用于治疗患有原发性动脉高血压和阻塞性睡眠呼吸暂停/低通气的青少年时的有效性。结果显示，CPAP治疗可根据患者的性别和年龄将动脉压水平降至正常或高正常范围。证实光疗对原发性高血压患者的昼夜节律系统产生有益影响。这些发现为推荐联合应用上述方法治疗患有原发性高血压和阻塞性睡眠呼吸暂停/低通气的青少年提供了依据。所提议的治疗方法能够通过纠正睡眠中的阻塞性呼吸障碍来降低动脉压，并使患有原发性高血压和阻塞性睡眠呼吸暂停/低通气的青少年的昼夜节律系统正常化。该方法的临床应用将有助于降低发病率、残疾发生率以及成年期并发症导致的死亡率。
