Valyshev A V
Zh Mikrobiol Epidemiol Immunobiol. 2014 Sep-Oct(5):119-26.
The main studies of a group of antimicrobial compounds produced by Enterococcus genus bacteria: bacteriocins, organic acids, activated oxygen metabolites, enzymes, exopolysaccharides--are described in the review. Data on synergic interaction of these substances in killing of pathogens, formation of active substances from different components as a result of metabolic activity of enterococci are presented. Production of these compounds is a reflection of competitive habitation of bacteria under the conditions of multi-species microbiomes and ensures colonization resistance of host biotopes. A complementation of the group of bacterial antimicrobial compounds by compounds that do not have a direct effect on the growth of microorganisms but suppress pathogenic potential of infectious disease causative agents is assumed.
细菌素、有机酸、活性氧代谢产物、酶、胞外多糖。文中介绍了这些物质在杀灭病原体方面的协同相互作用数据，以及由于肠球菌的代谢活性由不同成分形成活性物质的情况。这些化合物的产生反映了细菌在多物种微生物群落条件下的竞争性生存，并确保了宿主生物群落的定植抗性。假定一组细菌抗菌化合物可由对微生物生长无直接影响但能抑制传染病病原体致病潜力的化合物进行补充。
