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[国际妇产科联盟(FIGO)2009年子宫内膜癌分期I期的临床意义及其预后相关因素]

[Clinical significance of FIGO 2009 staging I and its prognostic related factors in endometrial carcinoma].

作者信息

Zhou Jingwei, Zhao Lijun, Qi Wenjuan, Li Xiaoping, Wang Jianliu, Wei Lihui

机构信息

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China. Email:

出版信息

Zhonghua Fu Chan Ke Za Zhi. 2014 Oct;49(10):776-9.

Abstract

OBJECTIVE

To discuss the clinical significance of Federation International of Gynecology and Obstetrics (FIGO) 2009 staging I and its prognostic related factors in endometrial carcinoma.

METHODS

A retrospective analysis was carried out on 233 cases with FIGO 2009 staging I endometrial carcinoma who were admitted to Department of Obstetrics and Gynecology, Peking University People's Hospital from Dec. 1998 to Dec. 2009 and were carried with complete staging operation then compared with FIGO 1988 staging. All follow-up data were complete.

RESULTS

Of the 233 cases, including FIGO 1988 staging I a 41 cases, I b 146 cases, I c 29 cases and II a 17 cases. The univariate analysis revealed that there were no significant difference between staging I a and I b group in histological grade, pathological type, intravascular vessel cancer embolus, the expression of ER, PR, postoperative chemotherapy or postoperative chemoradiotherapy (all P > 0.05). The univariate analysis revealed that there were no significant difference between staging I and II a group in histological grade, pathological type, intravascular vessel cancer embolus, the depth of myometrial invasion, the expression of ER and PR postoperative chemotherapy or postoperative chemoradiotherapy (all P > 0.05).

CONCLUSION

FIGO 2009 staging I in endometrial carcinoma is more consistent with the patient's clinical status than that in FIGO 1988 stage I and II a.

摘要

目的

探讨国际妇产科联盟(FIGO)2009分期I期子宫内膜癌的临床意义及其预后相关因素。

方法

回顾性分析1998年12月至2009年12月北京大学人民医院妇产科收治的233例FIGO 2009分期I期子宫内膜癌患者,均行完整分期手术,然后与FIGO 1988分期进行比较。所有随访资料完整。

结果

233例患者中,包括FIGO 1988分期I a期41例、I b期146例、I c期29例及II a期17例。单因素分析显示,I a期与I b期组在组织学分级、病理类型、血管内癌栓、ER、PR表达、术后化疗或术后放化疗方面差异均无统计学意义(均P>0.05)。单因素分析显示,I期与II a期组在组织学分级、病理类型、血管内癌栓、肌层浸润深度、ER和PR表达、术后化疗或术后放化疗方面差异均无统计学意义(均P>0.05)。

结论

与FIGO 1988分期I期和II a期相比,FIGO 2009分期I期子宫内膜癌更符合患者的临床状况。

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