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在液基细胞学宫颈样本中对伪装成宫颈腺癌的转移性卵巢癌进行直接采样。

Direct sampling of metastatic ovarian carcinoma masquerading as endocervical adenocarcinoma in liquid-based cytology cervical sample.

作者信息

Gupta Nalini, Bhar Vikrant, Dey Pranab, Rajwanshi Arvind, Suri Vanita

机构信息

Department of Cytology and Gynecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Cytol. 2014 Jul;31(3):165-7. doi: 10.4103/0970-9371.145654.

DOI:10.4103/0970-9371.145654
PMID:25538388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4274530/
Abstract

Cervical sample is routinely taken to identify squamous dysplastic lesions of the cervix. Glandular lesions are far less commonly reported on cervical samples. The most common glandular lesion reported on cervical smear is endocervical adenocarcinoma, followed by endometrial adenocarcinoma. Direct sampling by Cervex brush is possible even in endometrial adenocarcinoma, if the tumor directly involves lower uterine segment/endocervical canal. Metastases to cervix are rare but have occasionally been reported in previous reports. We wish to highlight in this case, metastatic ovarian carcinoma directly sampled in cervical liquid-based cytology (LBC) sample, which mimicked cytomorphologically a well-differentiated endocervical adenocarcinoma. To the best of our knowledge, a similar case has not been previously published in SurePath LBC sample.

摘要

常规采集宫颈样本以识别宫颈鳞状发育异常病变。宫颈样本中腺性病变的报告则要少得多。宫颈涂片报告中最常见的腺性病变是宫颈管腺癌,其次是子宫内膜腺癌。如果肿瘤直接累及子宫下段/宫颈管,即使是子宫内膜腺癌,也可以用宫颈刷直接取样。宫颈转移很少见,但既往报告中偶尔有过报道。我们希望在本病例中强调,在宫颈液基细胞学(LBC)样本中直接取样的转移性卵巢癌,其细胞形态学上类似于高分化宫颈管腺癌。据我们所知,类似病例此前尚未在SurePath LBC样本中发表过。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a89/4274530/badeb6aaa5c9/JCytol-31-165-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a89/4274530/7b5715b32065/JCytol-31-165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a89/4274530/badeb6aaa5c9/JCytol-31-165-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a89/4274530/7b5715b32065/JCytol-31-165-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a89/4274530/badeb6aaa5c9/JCytol-31-165-g002.jpg

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本文引用的文献

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Cytomorphological features of extra-genital metastases in SurePath™ cervical liquid-based cytology: a series of eight cases.SurePath™ 宫颈液基细胞学检查中生殖器外转移灶的细胞形态学特征:8例系列病例
Cytopathology. 2013 Apr;24(2):123-8. doi: 10.1111/j.1365-2303.2011.00945.x. Epub 2012 Jan 4.
2
Glandular neoplasia and borderline endocervical reporting rates before and after conversion to the SurePath(TM) liquid-based cytology (LBC) system.转换为SurePath™液基细胞学(LBC)系统前后的腺性肿瘤及宫颈内膜交界性病变报告率。
Diagn Cytopathol. 2011 Dec;39(12):869-74. doi: 10.1002/dc.21471. Epub 2010 Nov 2.
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Ovarian low-grade serous carcinoma involving the cervix mimicking a cervical primary.
宫颈低级别浆液性卵巢癌累及宫颈,类似于宫颈原发性肿瘤。
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Metastatic carcinomas in the cervix mimicking primary cervical adenocarcinoma and adenocarcinoma in situ: report of a series of cases.宫颈转移性癌酷似宫颈原发性腺癌和原位腺癌:一系列病例报道。
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Primary fallopian tubal transitional cell carcinoma with exfoliation of malignant cells in cervical Pap smear.原发性输卵管移行细胞癌伴宫颈巴氏涂片恶性细胞脱落
Cytojournal. 2005 Dec 9;2:20. doi: 10.1186/1742-6413-2-20.
6
Serous papillary cystadenocarcinoma of the ovary diagnosed with the ThinPrep Pap Test.经薄层液基细胞学检测诊断为卵巢浆液性乳头状囊腺癌。
Acta Cytol. 2000 Nov-Dec;44(6):1122-4.