Basu Reshma, Pathak Sunjay, Goyal Jyoti, Chaudhry Rajeev, Goel Rati B, Barwal Anil
Department of Critical Care, Sector-51, Gurgaon, Haryana, India.
Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
Indian J Crit Care Med. 2014 Dec;18(12):822-4. doi: 10.4103/0972-5229.146321.
CytoSorb(®) (CytoSorbents Corporation, USA) is a novel sorbent hemoadsorption device for cytokine removal. The aim of this study was to examine the clinical use of CytoSorb(®) in the management of patient with septic shock. We used this device as an adjuvant to stabilize a young patient with multi-organ failure and severe sepsis with septic shock. A 36-year-old female patient was hospitalized with the complaints of malaise, general body ache, and breathing difficulty and had a medical history of diabetes mellitus type II, hypertension, obstructive sleep apnea, hypothyroidism and morbid obesity. She was diagnosed to have septic shock with multi-organ dysfunction (MODS) and a low perfusion state. CytoSorb(®) hemoadsorption column was used as an attempt at blood purification. Acute physiology and chronic health evaluation score, MODS score, and sequential organ failure assessment score were measured before and after the device application. CytoSorb application as an adjuvant therapy could be considered in septic shock.
CytoSorb（®）（美国CytoSorbents公司）是一种用于清除细胞因子的新型吸附性血液净化装置。本研究的目的是探讨CytoSorb（®）在感染性休克患者治疗中的临床应用。我们将该装置用作辅助手段，以稳定一名患有多器官功能衰竭和严重脓毒症合并感染性休克的年轻患者的病情。一名36岁女性患者因全身乏力、周身疼痛和呼吸困难入院，有II型糖尿病、高血压、阻塞性睡眠呼吸暂停、甲状腺功能减退和病态肥胖病史。她被诊断为感染性休克伴多器官功能障碍（MODS）和低灌注状态。使用CytoSorb（®）血液吸附柱进行血液净化尝试。在应用该装置前后测量急性生理与慢性健康评估评分、MODS评分和序贯器官衰竭评估评分。在感染性休克中可考虑将CytoSorb作为辅助治疗手段。
