Karacavus Seyhan, Celik Ahmet, Tutus Ahmet, Kula Mustafa, Oguzhan Abdurrahman, Ozdogru Ibrahim, Kalay Nihat
Department of Nuclear Medicine, School of Medicine, Bozok University, Yozgat, Turkey.
Department of Cardiology, School of Medicine, Mersin University, Mersin, Turkey.
World J Nucl Med. 2014 Sep;13(3):184-9. doi: 10.4103/1450-1147.144819.
The purpose of this study is to compare the strain echocardiographic and scintigraphic parameters for evaluating of the left ventricular (LV) functions in patients with anterior myocardial infarction (MI). Fifty-four patients (male/female: 36/18; mean age 62 ± 13 years) with anterior MI were prospectively enrolled. All patients were performed gated myocardial perfusion scintigraphy gated single-photon emission computed tomography (GSPECT) and echocardiography (EC). GSPECT data were processed and analyzed using 4D-MSPECT (4DM, Invia Medical Imaging Solutions, Ann Arbor, MI, USA). The echocardiographic strain (S) and strain rate (SR) values were calculated. The results obtained by these techniques were compared each other. A total of 918 segments of LV wall were evaluated. In all patients, 385 segments were automatically scored as normokinetic, 206 as hypokinetic, 122 as akinetic, 205 as dyskinetic and 300 as normal thickening, 348 as decrease thickening and 270 as no thickening. The means of S and SR values in thickening and motion score groups according to GSPECT were statistically different from each other (P < 0.001). There was a negative significant correlation between LV wall thickening sum score and S and SR and between LV wall motion sum score and S and SR (P < 0.001). There was a good correlation between GSPECT and echocardiographic LV-ejection fraction (r = 0.7, P < 0.001). GSPECT and strain EC are similar in quantitative grading of the severity of regional and global myocardial dysfunction in patients with anterior MI and these techniques provide valuable diagnostic information.
本研究旨在比较应变超声心动图和闪烁扫描参数，以评估前壁心肌梗死（MI）患者的左心室（LV）功能。前瞻性纳入了54例前壁MI患者（男/女：36/18；平均年龄62±13岁）。所有患者均接受了门控心肌灌注闪烁扫描门控单光子发射计算机断层扫描（GSPECT）和超声心动图（EC）检查。使用4D-MSPECT（4DM，Invia Medical Imaging Solutions，美国密歇根州安阿伯）对GSPECT数据进行处理和分析。计算超声心动图应变（S）和应变率（SR）值。对这些技术获得的结果进行相互比较。共评估了918个左心室壁节段。在所有患者中，385个节段自动评分为运动正常，206个为运动减弱，122个为运动消失，205个为运动障碍，300个增厚正常，348个增厚减少，270个无增厚。根据GSPECT，增厚和运动评分组中S和SR值的均值在统计学上彼此不同（P<0.001）。左心室壁增厚总分与S和SR之间以及左心室壁运动总分与S和SR之间存在显著负相关（P<0.001）。GSPECT与超声心动图左心室射血分数之间存在良好的相关性（r = 0.7，P<0.001）。在评估前壁MI患者局部和整体心肌功能障碍的严重程度方面，GSPECT和应变超声心动图在定量分级上相似，且这些技术提供了有价值的诊断信息。
