Reed B D, Slattery M L, French T K
Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City.
J Fam Pract. 1989 Nov;29(5):509-15.
The association between dietary intake and the history of Candida vulvovaginitis was evaluated in 166 women who had a history of Candida vulvovaginitis in the past 5 years (cases) and in 207 women without such a history (total population), as well as in 74 women with five or more episodes in the past 5 years and 125 women with no history of Candida vulvovaginitis. Women were interviewed about their demographic data, past medical and sexual history, and their history of vaginal or pelvic infections. An extensive dietary history was taken to determine each woman's usual adult dietary intake. Results indicate associations between total caloric intake, carbohydrates, and fiber and a history of Candida vulvovaginitis. The results were not altered by controlling for age, body mass index, smoking, use of oral contraceptives, and sexual activity variables. These results suggest several dietary constituents may influence susceptibility to Candida vulvovaginitis infections. A follow-up prospective study, using culture confirmation of Candida infection, is needed.
在166名过去5年内有念珠菌性外阴阴道炎病史的女性(病例组)、207名无此病史的女性(总人群)以及74名过去5年内有5次或更多次发作的女性和125名无念珠菌性外阴阴道炎病史的女性中,评估了饮食摄入与念珠菌性外阴阴道炎病史之间的关联。研究人员询问了这些女性的人口统计学数据、既往病史和性病史,以及她们的阴道或盆腔感染史。还收集了详细的饮食史,以确定每位女性通常的成人饮食摄入量。结果表明,总热量摄入、碳水化合物和纤维与念珠菌性外阴阴道炎病史之间存在关联。在控制年龄、体重指数、吸烟、口服避孕药使用情况和性活动变量后,结果并未改变。这些结果表明,几种饮食成分可能会影响念珠菌性外阴阴道炎感染的易感性。需要进行一项后续前瞻性研究,采用念珠菌感染的培养确诊方法。