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分化型甲状腺癌的演变:单中心十年甲状腺切除术经验。

Evolution of differentiated thyroid cancer: a decade of thyroidectomies in a single institution.

机构信息

Department of Endocrinology, Universitat Autònoma de Barcelona, Spain ; Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.

Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.

出版信息

Eur Thyroid J. 2014 Sep;3(3):197-201. doi: 10.1159/000365416. Epub 2014 Aug 29.

DOI:10.1159/000365416
PMID:25538902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4224230/
Abstract

BACKGROUND

Numerous studies have shown an increase in the incidence of thyroid cancer (TC) in recent years.

OBJECTIVES

In this paper, we reviewed the incidence of TC in a series of patients undergoing thyroid surgery at a single institution over a 10-year period.

PATIENTS AND METHODS

The cohorts were divided into two periods (2001-2005 and 2006-2010) with the purpose of comparing various clinicopathologic variables.

RESULTS

A total of 1,263 patients were included. A significant increase in the number of malignancies was shown in the second period, namely 90 cases in 2001-2005 (15.2% of all interventions) compared to 163 cases in 2006-2010 (24.3%) (p < 0.001). These differences were attributed to an increase in papillary thyroid carcinoma (PTC), as there were 66 PTC cases in the first period (11.13% of thyroidectomies performed) compared to 129 cases in the second period (19.25%). There were no clinicohistological differences among PTC cases in these two periods.

CONCLUSIONS

Over the last decade, there has been an increase in the incidence of TC in patients undergoing thyroid surgery. This increase is exclusively due to increases in PTC. Our study verifies the existence of this trend in our geographical area, similar to that noted in other parts of the world.

摘要

背景

许多研究表明近年来甲状腺癌(TC)的发病率有所增加。

目的

本文回顾了一家医疗机构在 10 年期间对接受甲状腺手术的一系列患者的 TC 发病率。

患者和方法

将队列分为两个时期(2001-2005 年和 2006-2010 年),目的是比较各种临床病理变量。

结果

共纳入 1263 例患者。第二期的恶性肿瘤数量显著增加,即 2001-2005 年有 90 例(所有干预的 15.2%),而 2006-2010 年有 163 例(24.3%)(p < 0.001)。这些差异归因于乳头状甲状腺癌(PTC)的增加,因为在第一期有 66 例 PTC 病例(甲状腺切除术的 11.13%),而第二期有 129 例(19.25%)。在这两个时期的 PTC 病例中没有临床组织学差异。

结论

在过去十年中,接受甲状腺手术的 TC 患者的发病率有所增加。这种增加仅归因于 PTC 的增加。我们的研究证实了这种趋势在我们的地理区域存在,与世界其他地区的趋势相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2141/4224230/3153cef56337/etj-0003-0197-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2141/4224230/839b4d9b2d42/etj-0003-0197-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2141/4224230/3153cef56337/etj-0003-0197-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2141/4224230/839b4d9b2d42/etj-0003-0197-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2141/4224230/3153cef56337/etj-0003-0197-g02.jpg

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The epidemic of thyroid cancer in the United States: the role of endocrinologists and ultrasounds.美国甲状腺癌的流行:内分泌学家及超声检查的作用
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