Zhang Feng, Zhang Xiaojian, Zhang Xin, Chen Bo, Liu Yukun, Yue Wen-Wei, Jia Ru-Yi
The Fourth People's Hospital of Ji'nan, Ji'nan, 250031, China.
Shandong Provincial Hospital, Shandong University, Shandong, China.
Cell Biochem Biophys. 2015 May;72(1):127-30. doi: 10.1007/s12013-014-0419-1.
As an important parameter of cardiac functions, QT interval is usually irregular in patients with chronic coronary artery total occlusion (CTO). We sought to determine the effect of coronary revascularization (CRV) on QT interval dispersion in patients with CTO. To this end, we used electrocardiogram of 12 leads to record changes in the QT interval dispersion in 22 patients with CTO treated with percutaneous coronary intervention (PCI) and 24 patients treated with coronary artery bypass grafting (CABG). Our data showed that QTd and QTcd diminished markedly (P < 0.01) after PCI or CABG. No significant difference was observed between the postoperative groups (P > 0.05) or between PCI and CABG groups. We concluded that CRV could diminish QTd and QTcd in patients with CTO with no distinguishable differences with PCI and CABG procedures. Therefore, CRV can revitalize the existing functional myocardium and resume the myocardial electrophysiological functions in patients with CTO.
作为心脏功能的一个重要参数，QT间期在慢性冠状动脉完全闭塞（CTO）患者中通常是不规则的。我们试图确定冠状动脉血运重建（CRV）对CTO患者QT间期离散度的影响。为此，我们使用12导联心电图记录了22例接受经皮冠状动脉介入治疗（PCI）的CTO患者和24例接受冠状动脉旁路移植术（CABG）的患者的QT间期离散度变化。我们的数据显示，PCI或CABG术后QTd和QTcd显著降低（P<0.01）。术后组之间（P>0.05）或PCI与CABG组之间未观察到显著差异。我们得出结论，CRV可以降低CTO患者的QTd和QTcd，PCI和CABG手术之间没有明显差异。因此，CRV可以使CTO患者现存的功能性心肌恢复活力，并恢复心肌电生理功能。
