Weems Phillip, Cooper Matthew
Phillip Weems, Matthew Cooper, MedStar Georgetown Transplant Institute, Washington, DC 20007, United States.
World J Transplant. 2014 Dec 24;4(4):216-21. doi: 10.5500/wjt.v4.i4.216.
Although the diagnosis of type 2 diabetes mellitus was once considered a contraindication to simultaneous pancreas-kidney transplantation, a growing body of evidence has revealed that similar graft and patient survival can be achieved when compared to type 1 diabetes mellitus recipients. A cautious strategy regarding candidate selection may limit appropriate candidates from additional benefits in terms of quality of life and potential amelioration of secondary side effects of the disease process. Although our current understanding of the disease has changed, uniform listing characteristics to better define and study this population have limited available data and must be established.
尽管2型糖尿病的诊断曾一度被视为同期胰肾联合移植的禁忌证，但越来越多的证据表明，与1型糖尿病受者相比，2型糖尿病受者可获得相似的移植物和患者存活率。在候选者选择方面采取谨慎策略可能会使合适的候选者无法从生活质量的改善及疾病进程潜在继发性副作用的缓解中获得更多益处。尽管我们目前对该疾病的认识已经改变，但用于更好地定义和研究这一人群的统一列入标准却因可用数据有限而必须加以确立。
