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多相阳极火花沉积处理的多孔钛植入物在绵羊模型中的骨整合。

Osseointegration of multiphase anodic spark deposition treated porous titanium implants in an ovine model.

作者信息

Bertollo Nicky, Sandrini Enrico, Dalla Pria Paolo, Walsh William R

机构信息

Surgical & Orthopaedic Research Laboratories, University of New South Wales, Prince of Wales Hospital Clinical School, Sydney, Australia.

SAMO Spa, Granarolo Emilia, Bologna, Italy.

出版信息

J Arthroplasty. 2015 Mar;30(3):484-8. doi: 10.1016/j.arth.2013.10.003. Epub 2013 Oct 16.

DOI:10.1016/j.arth.2013.10.003
PMID:25540993
Abstract

Modification of titanium oxide by multiphase anodic spark deposition (ASD) has the potential to increase bioactivity and hasten osseointegration and biological fixation in uncemented arthroplasty. This study assessed the in vivo performance of control (Ti), plasma-sprayed HA-coated (TiHA) and ASD (Biospark) treated (TiAn) porous titanium implants with a solid core using a standard uncemented implant fixation sheep model. Cortical interfacial shear-strength and bone ingrowth in cortical and cancellous sites were quantified following 12 weeks in situ. Ultimate shear-strength for the Ti, TiHA and TiAn coatings was 33±9.5, 35.4±8.4 and 33.8±7.8 MPa, respectively, which was limited by coating delamination. ASD treatment was associated with significantly higher mean bone ingrowth at both sites. These results support the osteoconductive potential of the BioSpark treatment of porous titanium.

摘要

通过多相阳极火花沉积(ASD)对二氧化钛进行改性,有可能提高生物活性,并加速非骨水泥关节成形术中的骨整合和生物固定。本研究使用标准的非骨水泥植入物固定绵羊模型,评估了实心核心的对照(Ti)、等离子喷涂HA涂层(TiHA)和ASD(生物火花)处理(TiAn)的多孔钛植入物的体内性能。在原位放置12周后,对皮质界面剪切强度以及皮质和松质部位的骨长入情况进行了量化。Ti、TiHA和TiAn涂层的极限剪切强度分别为33±9.5、35.4±8.4和33.8±7.8MPa,均受涂层分层限制。ASD处理与两个部位显著更高的平均骨长入相关。这些结果支持了生物火花处理多孔钛的骨传导潜力。

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