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心脏直视手术后早期纳入门诊心脏康复的安全性。

Safety of early enrollment into outpatient cardiac rehabilitation after open heart surgery.

作者信息

Pack Quinn R, Dudycha Kent J, Roschen Kyle P, Thomas Randal J, Squires Ray W

机构信息

Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota; Division of Cardiology, Baystate Medical Center, Springfield, Massachusetts; Clinical and Translational Science Institute, Tufts University School of Medicine, Boston, Massachusetts.

Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota.

出版信息

Am J Cardiol. 2015 Feb 15;115(4):548-52. doi: 10.1016/j.amjcard.2014.11.040. Epub 2014 Nov 29.

Abstract

The safety of early enrollment (<2 weeks after hospital discharge) into cardiac rehabilitation (CR) after recent coronary artery bypass graft (CABG) surgery or heart valve surgery (HVS) has not previously been assessed and has important policy implications. Consequently, we performed a detailed review of all clinical adverse events within 6 months of hospital discharge. We compared early and late attendees for patients undergoing CABG surgery or HVS and included patients with myocardial infarction (MI) as an additional control group. We analyzed 112 patients undergoing CABG surgery, 69 patients undergoing HVS, and 59 patients with MI. Median time (interquartile range) from hospital discharge to CR enrollment was 10.5 (8 to 15), 12 (8.5 to 21), and 9 days (7 to 14), respectively. There was no difference in major event rates between early and late enrollees (17% vs 17%, respectively, log-rank p = 0.98) or by diagnosis (15%, 16%, and 22% for CABG surgery, HVS, and MI, respectively; log-rank p = 0.50). Sternal instability and wound infection rates were similar. CR-related adverse events trended toward increased event rates in surgical and early enrollees, but of 44 events, only 3 were exercise related, none resulted in permanent harm, and 41 (93%) were managed in CR without need for emergency services. In conclusion, it appears that a policy of encouraging early enrollment into CR in patients with a recent open heart surgery seems unlikely to harm patients when careful individualized assessment and exercise prescription take place within the bounds of an established CR program.

摘要

近期冠状动脉旁路移植术(CABG)或心脏瓣膜手术(HVS)后早期(出院后<2周)参加心脏康复(CR)的安全性此前尚未得到评估,且具有重要的政策意义。因此,我们对出院后6个月内的所有临床不良事件进行了详细回顾。我们比较了接受CABG手术或HVS的患者早期和晚期参与者,并将心肌梗死(MI)患者作为额外的对照组。我们分析了112例接受CABG手术的患者、69例接受HVS的患者和59例MI患者。从出院到参加CR的中位时间(四分位间距)分别为10.5天(8至15天)、12天(8.5至21天)和9天(7至14天)。早期和晚期参与者之间的主要事件发生率没有差异(分别为17%和17%,对数秩检验p = 0.98),按诊断分类也没有差异(CABG手术、HVS和MI分别为15%、16%和22%;对数秩检验p = 0.50)。胸骨不稳定和伤口感染率相似。CR相关不良事件在手术患者和早期参与者中事件发生率有上升趋势,但在44起事件中,只有3起与运动相关,均未导致永久性伤害,41起(93%)在CR中得到处理,无需紧急服务。总之,在既定的CR计划范围内进行仔细的个体化评估和运动处方时,鼓励近期接受心脏直视手术的患者早期参加CR的政策似乎不太可能对患者造成伤害。

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