Wikonkál Norbert, Nagy Patrícia, Tóth Béla, Marschalkó Márta, Tislér András, Kárpáti Sarolta
Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
Semmelweis Egyetem, Általános Orvostudományi Kar I. Belgyógyászati Klinika Budapest.
Orv Hetil. 2015 Jan 4;156(1):32-5. doi: 10.1556/OH.2015.30082.
The authors report the history of a patient with syphilitic glomerulonephritis, a rare complication of syphilis. The patient was admitted to the hospital with clinical symptoms of neurosyphilis. During his hospital stay urine analysis revealed an extremely high proteinuria, that had not been known before. Intravenous penicillin treatment improved the renal protein loss, but it took a total of six months until complete resolution was achieved. The serology that confirmed the syphilis, the concomitant nephrotic syndrome and the improvement after penicillin therapy met the criteria of syphilitic glomerulonephritis. This case prompted the authors to review the literature about this rare complication of syphilis that has a great clinical significance.
作者报告了一例梅毒肾小球肾炎患者的病史,梅毒肾小球肾炎是梅毒一种罕见的并发症。该患者因神经梅毒的临床症状入院。住院期间尿液分析显示出极高的蛋白尿,此前并不知晓。静脉注射青霉素治疗改善了肾脏蛋白质流失,但总共花了六个月才完全恢复。确诊梅毒的血清学检查、并发的肾病综合征以及青霉素治疗后的改善情况均符合梅毒肾小球肾炎的标准。该病例促使作者回顾了关于梅毒这一具有重大临床意义的罕见并发症的文献。