Gelaw Belayneh Kefale, Mohammed Abdela, Tegegne Gobezie Temesgen, Defersha Amsalu Degu, Fromsa Muluneh, Tadesse Esayas, Gunasekaran Thrumurgan, Ahmed Mustefa
Department of Pharmacy, College of Medicine and Health Science, Ambo University, Oromia Region, Ethiopia.
J Diabetes Res. 2014;2014:617041. doi: 10.1155/2014/617041. Epub 2014 Dec 3.
The objective of this study was to determine the magnitude of nonadherence and its contributing factors among diabetic patients attending the diabetic clinic in Adama Hospital.
This descriptive cross-sectional study was carried out among patients with diabetes mellitus attending the diabetes mellitus clinic of Adama Referral Hospital. Every other patient was selected and data regarding their medication adherence was collected using a structured interview. Data analysis was carried out using SPSS-16.
The response rate from this study was 98.3%. A total of 270 patients were interviewed; 51.5% were males. A total of 68.1% of the patients included in the study were married. 14% were younger than 40 years, and 50% were between 40 and 60 years. 21.8% of the participants ascribed their nonadherence to forgetting to take their medications. Patients with duration of diabetes ≤5 years (82.07%) were more compliant to their medication than those with >5 years (60.8%), which was found to be statistically significant (P = 0.003). Insulin, 47%, and glibenclamide plus metformin, 43.7%, were the most commonly prescribed mono- and combination therapies, respectively. Common comorbid conditions include hypertension, 148 (54.82%), and visual impairment, 89 (32.96%). The proportion of male patients adherent to their antidiabetic medications was found to be lower than 69.78% compared to the female patients (74.81%), but the difference was not statistically significant (P > 0.05).
Most diabetic patients are currently being managed with the most effective available drugs. However the result from this study indicates that the desired blood sugar level could not be controlled and maintained adequately. This was because of poor adherence to the prescribed drug regimen and poor knowledge and practice of successful self-management.
本研究的目的是确定阿达马医院糖尿病门诊糖尿病患者的不依从程度及其影响因素。
本描述性横断面研究在阿达马转诊医院糖尿病门诊的糖尿病患者中进行。每隔一名患者被选中，并通过结构化访谈收集有关他们药物依从性的数据。使用SPSS - 16进行数据分析。
本研究的应答率为98.3%。共访谈了270名患者；51.5%为男性。纳入研究的患者中，68.1%已婚。14%年龄小于40岁，50%年龄在40至60岁之间。21.8%的参与者将其不依从归因于忘记服药。糖尿病病程≤5年的患者（82.07%）比病程>5年的患者（60.8%）对药物的依从性更高，差异具有统计学意义（P = 0.003）。胰岛素（47%）和格列本脲加二甲双胍（43.7%）分别是最常用的单一疗法和联合疗法。常见的合并症包括高血压（148例，54.82%）和视力障碍（89例，32.96%）。发现男性糖尿病患者对抗糖尿病药物的依从率低于女性患者（74.81%），为69.78%，但差异无统计学意义（P > 0.05）。
目前大多数糖尿病患者正在使用最有效的现有药物进行治疗。然而，本研究结果表明，无法充分控制和维持理想的血糖水平。这是因为对规定的药物治疗方案依从性差，以及成功自我管理的知识和实践不足。
