*Department of Dermatology, Mayo Clinic, Rochester, Minnesota; †Mayo Medical School, Mayo Clinic, Rochester, Minnesota.
Dermatol Surg. 2015 Jan;41(1):69-77. doi: 10.1097/DSS.0000000000000208.
Two repair options for Mohs defects of the helix include full-thickness skin grafting and second-intention healing. Limited long-term data exist comparing these 2 repair options.
To compare outcomes of full-thickness skin grafts (FTSG) versus second-intention wound healing for Mohs defects on the helix.
In this study, 29 second-intention and 18 FTSG repairs were evaluated using a visual analog scale (VAS). Patient questionnaires and retrospective chart analysis were used to assess secondary outcomes.
The average second-intention VAS score was 82.1 (standard deviation [SD] = 7.6), and the average FTSG VAS score was 75.2 (SD = 16.7) (difference of 6.9, 95% confidence interval: -1.3 to 15.1, p = .061). A subsequent noninferiority test indicated that cosmetic outcome of second-intention healing was at least as good as that of FTSG in the authors' study (p < .001). Retrospective chart analysis revealed no significant difference in complications. Patient-reported outcomes were not significantly different.
Mohs surgical defects of the helix left to heal by second-intention have comparable long-term cosmetic outcomes to those repaired by FTSG. There was no significant difference in complications, and patients were highly satisfied with both repair options.
修复耳廓 Mohs 缺损的两种方法包括全厚皮片移植和二期愈合。比较这两种修复方法的长期数据有限。
比较全厚皮片移植（FTSG）与二期愈合修复耳廓 Mohs 缺损的效果。
本研究使用视觉模拟评分（VAS）对 29 例二期愈合和 18 例 FTSG 修复进行评估。通过患者问卷调查和回顾性图表分析评估次要结果。
二期愈合的平均 VAS 评分为 82.1（标准差 [SD] = 7.6），FTSG 的平均 VAS 评分为 75.2（SD = 16.7）（差值为 6.9，95%置信区间：-1.3 至 15.1，p =.061）。随后的非劣效性检验表明，在本研究中，二期愈合的美容效果至少与 FTSG 相当（p <.001）。回顾性图表分析显示并发症无显著差异。患者报告的结果无显著差异。
耳廓 Mohs 手术缺损采用二期愈合的长期美容效果与 FTSG 修复相当。两种修复方法的并发症无显著差异，患者对两种修复方法均高度满意。
