Pant Chaitanya, Sferra Thomas J, Olyaee Mojtaba, Gilroy Richard, Anderson Michael P, Rastogi Amit, Pandya Prashant K, Deshpande Abhishek
Division of Gastroenterology, Hepatology and Motility, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS.
Acad Emerg Med. 2015 Jan;22(1):117-9. doi: 10.1111/acem.12552. Epub 2014 Dec 24.
The objective was to estimate emergency department (ED) visits for Clostridium difficile infection in the United States for the years 2006 through 2010.
Estimates of ED visits for C. difficile infection were calculated in patients 18 years and older using the Nationwide Emergency Department Sample.
During the calendar years 2006 through 2010, there were an estimated total of 491,406,018 ED visits. Of these, 462,160 ED visits were associated with a primary International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis of C. difficile. The C. difficile infection ED visit rate (visits/100,000 census population) increased from 34.1 in 2006 to 42.3 in 2010, an increase of 24% (p < 0.01). There was also a significant overall increased trend in the number of ED visits for C. difficile from 2006 through 2010 (p < 0.01). The highest ED visit rate for C. difficile was observed for patients 65 years and older (163.18 per 100,000), while the lowest visit rate was for patients aged 18 to 24 years (5.10 per 100,000). The greatest increase in C. difficile infection visits occurred in the age group 18 to 24 years.
These results indicate an increased trend of ED visits for C. difficile in the period 2006 through 2010 with an overall population-adjusted increase of 24%. This represents important complementary data to previous studies reporting an increase in the rate of C. difficile infections in the U.S. hospitalized population.
本研究旨在估算2006年至2010年期间美国急诊科艰难梭菌感染就诊病例数。
采用全国急诊科样本，计算18岁及以上患者艰难梭菌感染的急诊科就诊估算值。
在2006年至2010年期间，估计急诊科就诊总数为491,406,018人次。其中，462,160人次就诊与国际疾病分类第九版临床修订本中艰难梭菌的主要诊断相关。艰难梭菌感染的急诊科就诊率（每10万人口就诊人次）从2006年的34.1上升至2010年的42.3，增长了24%（p<0.01）。2006年至2010年期间，艰难梭菌感染的急诊科就诊人次也呈现出显著的总体上升趋势（p<0.01）。65岁及以上患者的艰难梭菌感染急诊科就诊率最高（每10万人中163.18人次），而18至24岁患者的就诊率最低（每10万人中5.10人次）。艰难梭菌感染就诊人次增长幅度最大的是18至24岁年龄组。
这些结果表明，2006年至2010年期间，艰难梭菌感染的急诊科就诊呈上升趋势，总体经人口调整后增长了24%。这为之前报道美国住院患者中艰难梭菌感染率上升的研究提供了重要的补充数据。
