Barrado Solís Nerea, Molés Poveda Paula, Lloret Ruiz César, Pont Sanjuan Virginia, Velasco Pastor Manel, Quecedo Estébanez Esther, Miquel Miquel Javier
Department of Dermatology, Arnau de Vilanova Hospital, Valencia, Spain.
Dermatol Ther. 2015 Mar-Apr;28(2):79-82. doi: 10.1111/dth.12188. Epub 2014 Dec 29.
Actinic cheilitis (AC) are premalignant lesions that have an increased risk of malignant transformation. Their treatment, therefore, is essential to prevent carcinogenesis. However, optimal therapy is not well established and different modalities yield variable results. Ingenol mebutate gel has recently been approved by the US Food and Drug Administration for topical treatment of actinic keratosis, with high clearance rates. On the basis of these findings, we report our experience with this drug for the treatment of AC.
光化性唇炎（AC）是具有恶变风险增加的癌前病变。因此，对其进行治疗对于预防癌变至关重要。然而，最佳治疗方法尚未明确确立，不同的治疗方式产生的效果也各不相同。鬼臼毒素凝胶最近已被美国食品药品监督管理局批准用于光化性角化病的局部治疗，清除率很高。基于这些发现，我们报告了我们使用这种药物治疗AC的经验。
