Heye Tobias, Sommer Gregor, Miedinger David, Bremerich Jens, Bieri Oliver
Cardiothoracic Section, Department of Radiology and Nuclear Medicine, University Hospital Basel, Switzerland.
Swiss National Insurance Fund SUVA, Luzern, Switzerland.
J Magn Reson Imaging. 2015 Sep;42(3):602-9. doi: 10.1002/jmri.24836. Epub 2014 Dec 27.
To evaluate the anatomical details offered by a new single breath-hold ultrafast 3D balanced steady-state free precession (uf-bSSFP) sequence in comparison to low-dose chest computed tomography (CT).
This was an Institutional Review Board (IRB)-approved, Health Insurance Portability and Accountability Act (HIPAA)-compliant prospective study. A total of 20 consecutive patients enrolled in a lung cancer screening trial underwent same-day low-dose chest CT and 1.5T MRI. The presence of pulmonary nodules and anatomical details on 1.9 mm isotropic uf-bSSFP images was compared to 2 mm lung window reconstructions by two readers. The number of branching points on six predefined pulmonary arteries and the distance between the most peripheral visible vessel segment to the pleural surface on thin slices and 50 mm maximum intensity projections (MIP) were assessed. Image quality and sharpness of the pulmonary vasculature were rated on a 5-point scale.
The uf-bSSFP detection rate of pulmonary nodules (32 nodules visible on CT and MRI, median diameter 3.9 mm) was 45.5% with 21 false-positive findings (pooled data of both readers). Uf-bSSFP detected 71.2% of branching points visible on CT data. The mean distance between peripheral vasculature and pleural surface was 13.0 ± 4.2 mm (MRI) versus 8.5 ± 3.3 mm (CT) on thin slices and 8.6 ± 3.9 mm (MRI) versus 4.6 ± 2.5 mm (CT) on MIPs. Median image quality and sharpness were rated 4 each.
Although CT is superior to MRI, uf-bSSFP imaging provides good anatomical details with sufficient image quality and sharpness obtainable in a single breath-hold covering the entire chest.
与低剂量胸部计算机断层扫描（CT）相比，评估一种新的单次屏气超快三维平衡稳态自由进动（uf-bSSFP）序列所提供的解剖细节。
这是一项经机构审查委员会（IRB）批准、符合《健康保险流通与责任法案》（HIPAA）的前瞻性研究。共有20名连续参加肺癌筛查试验的患者在同一天接受了低剂量胸部CT和1.5T磁共振成像（MRI）检查。两名阅片者将1.9毫米各向同性uf-bSSFP图像上的肺结节和解剖细节与2毫米肺窗重建图像进行了比较。评估了六条预定义肺动脉上的分支点数，以及薄层图像和50毫米最大密度投影（MIP）上最外周可见血管段到胸膜表面的距离。肺血管的图像质量和清晰度按5分制进行评分。
肺结节的uf-bSSFP检测率（CT和MRI上可见32个结节，中位直径3.9毫米）为45.5%，有21例假阳性结果（两名阅片者的汇总数据）。Uf-bSSFP检测到了CT数据上可见的71.2%的分支点。薄层图像上，外周血管与胸膜表面的平均距离为13.0±4.2毫米（MRI）对8.5±3.3毫米（CT），MIP上为8.6±3.9毫米（MRI）对4.6±2.5毫米（CT）。图像质量和清晰度的中位数评分均为4分。
尽管CT优于MRI，但uf-bSSFP成像能提供良好的解剖细节，具有足够的图像质量和清晰度，且可在单次屏气下覆盖整个胸部。
