8种不同无针静脉输液接入装置微生物侵入情况的体外比较。

An in vitro comparison of microbial ingress into 8 different needleless IV access devices.

作者信息

Casey Anna, Karpanen Tarja, Nightingale Peter, Elliott Tom

机构信息

University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom. Anna Casey, PhD, BSc, is affiliated with the Department of Clinical Microbiology, University Hospitals Birmingham NHS Foundation Trust in Birmingham, United Kingdom, and has 13 years of experience in clinical research. She holds a PhD in the prevention and diagnosis of central venous catheter-related infection. Tarja Karpanen, PhD, BSc, RGN, has 15 years of experience as a nurse, mainly in critical care, and more than 8 years' experience in research. She holds a PhD in the improvement of skin antisepsis. Dr. Karpanen works in the Department of Clinical Microbiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom. Peter Nightingale, PhD, BSc, is a statistician who has worked in health care for 25 years. He is affiliated with the Wolfson Computer Laboratory, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom. Tom Elliott, PhD, DSc, MRCP, BM, BS, BMedSci, FRCPath, has been a consultant microbiologist for 28 years and has served on many national and international advisory boards and expert groups. His main area of interest is the prevention and management of prosthetic device infections. Dr. Elliott is affiliated with the Department of Clinical Microbiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

出版信息

J Infus Nurs. 2015 Jan-Feb;38(1):18-25. doi: 10.1097/NAN.0000000000000082.

DOI:10.1097/NAN.0000000000000082

PMID:25545971

Abstract

There are conflicting reports of the effect needleless intravenous access devices have on rates of catheter-related bloodstream infection. The aim of this study was to identify any differences between the rates of microbial ingress into 8 different devices following contamination. Each type of device was subjected to a 7-day clinical simulation that involved repeated microbial contamination of the injection site and decontamination followed by saline flushes. Significant differences in the number of microorganisms associated with each device were detected in the saline eluates. Three positive-displacement mechanical valves were associated with the ingress of significantly fewer microorganisms compared with other devices.

摘要

关于无针静脉输液装置对导管相关血流感染发生率的影响，存在相互矛盾的报告。本研究的目的是确定8种不同装置在污染后微生物侵入率之间的差异。每种装置都经历了为期7天的临床模拟，包括对注射部位进行反复的微生物污染、去污，然后用盐水冲洗。在盐水洗脱液中检测到与每种装置相关的微生物数量存在显著差异。与其他装置相比，三种正位移机械阀与显著较少的微生物侵入相关。