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皮下免疫球蛋白替代疗法:确保成功。

Subcutaneous immunoglobulin replacement therapy: ensuring success.

作者信息

Younger M Elizabeth M, Blouin William, Duff Carla, Epland Kristin Buehler, Murphy Elyse, Sedlak Debra

机构信息

Johns Hopkins University School of Medicine, Baltimore, Maryland (Dr Younger); Miami Children's Hospital, Miami, Florida (Mr Blouin); University of South Florida/All Children's Hospital, St. Petersburg, Florida (Ms Duff); Midwest Immunology Clinic, Plymouth, Minnesota (Ms Epland); and CSL Behring, King of Prussia, Pennsylvania (Ms Murphy); and Duke University Medical Center, Durham, North Carolina (Ms Sedlak). M. Elizabeth M. Younger, PhD, CRNP, is an assistant professor of pediatrics and a pediatric nurse practitioner in the Division of Pediatric Immunology at Johns Hopkins University School of Medicine in Baltimore, Maryland. She has extensive experience with managing immunoglobulin therapy for antibody-deficient patients. William Blouin, MSN, ARNP, CPNP, works in pediatric allergy and immunology at Miami Children's Hospital, Miami, Florida. With more than 35 years of experience in pediatrics, his interests and expertise are allergy, human immunodeficiency virus, immunology, infusion, and transplantation. Carla Duff, MSN, CPNP, CCRP, is a nurse practitioner in pediatric allergy and immunology at the University of South Florida/All Children's Hospital, St. Petersburg, Florida. She has many years of experience with clinical immunology and managing immunoglobulin replacement therapy for primary immunodeficiency patients. Kristin Buehler Epland, MSN, FNP, is a family nurse practitioner specializing in the care and diagnosis of primary immunodeficiencies and autoimmune diseases at Midwest Immunology Clinic, Plymouth, Minnesota. She has worked with immunodeficient patients through home and clinic infusion nursing. Elyse Murphy, BSN, RN, is a medical science liaison with CSL Behring in King of Prussia, Pennsylvania, and has more than 30 years of expertise in immunoglobulin therapies in immunology, hematology-oncology, neurology, and transplant therapeutic areas. Debra Sedlak, CPNP, has more than 30 years of experience in clinical immunology in the Division of Pediatric A

出版信息

J Infus Nurs. 2015 Jan-Feb;38(1):70-9. doi: 10.1097/NAN.0000000000000087.

DOI:10.1097/NAN.0000000000000087
PMID:25545976
Abstract

Subcutaneous immunoglobulin (SCIg) infusions are an option for patients requiring immunoglobulin therapy. Nurses are uniquely positioned to advocate for patients and to teach them how to successfully manage their infusions. The purpose of this review is to describe SCIg therapy and to provide teaching instructions as well as creative tips to ensure treatment success.

摘要

皮下注射免疫球蛋白(SCIg)输注是需要免疫球蛋白治疗的患者的一种选择。护士在为患者提供支持以及教导他们如何成功管理输注方面具有独特的地位。本综述的目的是描述SCIg治疗,并提供教学指导以及创新小贴士,以确保治疗成功。

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Subcutaneous immunoglobulin replacement therapy: ensuring success.皮下免疫球蛋白替代疗法:确保成功。
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引用本文的文献

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Exploring Multidimensional Risk Factors Associated with Local Adverse Reactions to Subcutaneous Immunoglobulin Therapy: Insights from a Nationwide Multicenter Study.探索与皮下免疫球蛋白治疗局部不良反应相关的多维风险因素:一项全国性多中心研究的见解
Biomedicines. 2025 Aug 15;13(8):1991. doi: 10.3390/biomedicines13081991.
2
Patient Experience and Improvement Opportunities in Self-Administered, Large-Volume Subcutaneous Infusions at Home.居家自行进行大容量皮下注射的患者体验及改进机会
Patient Prefer Adherence. 2025 Aug 13;19:2459-2491. doi: 10.2147/PPA.S515565. eCollection 2025.
3
Home-based subcutaneous immunoglobulin for chronic inflammatory demyelinating polyneuropathy patients: A Swiss cost-minimization analysis.
家庭皮下免疫球蛋白治疗慢性炎症性脱髓鞘性多发性神经病患者:一项瑞士成本最小化分析。
PLoS One. 2020 Nov 25;15(11):e0242630. doi: 10.1371/journal.pone.0242630. eCollection 2020.
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Low-dose subcutaneous immunoglobulin is an effective treatment for autoimmune bullous skin disorders: A case report.低剂量皮下注射免疫球蛋白是自身免疫性大疱性皮肤病的有效治疗方法:病例报告
SAGE Open Med Case Rep. 2020 Jan 21;8:2050313X19901071. doi: 10.1177/2050313X19901071. eCollection 2020.
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Intravenous immunoglobulin therapy: a snapshot for the internist.静脉注射免疫球蛋白治疗:内科医生的快照。
Intern Emerg Med. 2019 Oct;14(7):1041-1049. doi: 10.1007/s11739-019-02150-z. Epub 2019 Jul 15.
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II Brazilian Consensus on the use of human immunoglobulin in patients with primary immunodeficiencies.二、巴西关于原发性免疫缺陷患者使用人免疫球蛋白的共识
Einstein (Sao Paulo). 2017;15(1):1-16. doi: 10.1590/S1679-45082017AE3844.