Segev Fani, Mimouni Michael, Tessler Gili, Hilely Assaf, Ofir Shay, Kidron Deborah, Bahar Irit
a Department of Ophthalmology , Meir Medical Center , Kfar Sava , Israel .
b The Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel .
Curr Eye Res. 2015;40(12):1284-7. doi: 10.3109/02713683.2014.993086. Epub 2014 Dec 29.
It is essential to assess the yield of routine histopathological examination of pterygium specimens excised from clinically benign pterygium. The purpose of this study was to determine the rate of histopathologically identified ocular surface squamous neoplasia (OSSN) in clinically benign pterygium specimens.
This retrospective consecutive study consisted of patients from the cornea services of the ophthalmology departments of Meir Medical Center, Kfar Sava, and Rabin Medical Center, Petah Tikva, Israel. Included patients were those with clinically benign pterygium who underwent pterygium excision between January 2002 and December 2011. The pterygium specimens were sent for histopathological examination and the pathology reports were reviewed for evidence of OSSN.
Overall, pathology reports of 682 eyes of 585 sequential patients were included in the study. There was a male predominance of cases (59%). Patients' age ranged from 16 to 87 years with an average age of 56 years. Six hundred and forty-three cases were primary (94%) and 39 cases were recurrent (6%).
Cases of clinically benign pterygium diagnosed and excised by an experienced corneal expert are less likely to harbor OSSN. The yield of routine histopathological examination of such specimens may be low.
评估从临床诊断为良性翼状胬肉切除的标本进行常规组织病理学检查的结果很有必要。本研究的目的是确定临床诊断为良性的翼状胬肉标本中经组织病理学鉴定的眼表鳞状上皮肿瘤（OSSN）的发生率。
这项回顾性连续研究纳入了来自以色列卡法萨瓦的梅尔医疗中心和佩塔提克瓦的拉宾医疗中心眼科角膜科的患者。纳入的患者为2002年1月至2011年12月期间接受翼状胬肉切除术的临床诊断为良性翼状胬肉的患者。将翼状胬肉标本送去进行组织病理学检查，并审查病理报告以寻找OSSN的证据。
总体而言，本研究纳入了585例连续患者的682只眼的病理报告。病例以男性居多（59%）。患者年龄在16至87岁之间，平均年龄为56岁。643例为原发性（94%），39例为复发性（6%）。
由经验丰富的角膜专家诊断并切除的临床诊断为良性的翼状胬肉病例发生OSSN的可能性较小。此类标本常规组织病理学检查的检出率可能较低。
