Pomaskin I N, Medvedev B I, Tsirkin V I, Zakharov V V
Akush Ginekol (Mosk). 1989 Aug(8):23-7.
In order to reveal endogenous beta-adrenomimetic in the blood the authors proposed the biological testing of the serum and plasma on the isolated myometrium of the rat. For this purpose obsidan was used as a beta-adrenoblocker. It was shown that endogenous beta-adrenomimetic different from adrenaline was present in the blood of males, nonpregnant and pregnant females and parturients. Besides, its concentration increased in pregnancy and remained high early in labor.
为了揭示血液中的内源性β-肾上腺素能物质，作者提出对大鼠离体子宫肌层进行血清和血浆的生物学检测。为此，使用氧烯洛尔作为β-肾上腺素能阻滞剂。结果表明，雄性、未孕和孕龄雌性以及产妇的血液中存在不同于肾上腺素的内源性β-肾上腺素能物质。此外，其浓度在怀孕期间升高，并在分娩早期保持在较高水平。
