[内源性β-肾上腺素能拟似物质作为肾上腺素能β受体阻断机制的一个组成部分]
[Endogenous beta-adrenomimetic substance as a constituent of the adrenergic beta receptor blocking mechanism].
作者信息
Pomaskin I N, Medvedev B I, Tsirkin V I, Zakharov V V
出版信息
Akush Ginekol (Mosk). 1989 Aug(8):23-7.
PMID:2554739
Abstract
In order to reveal endogenous beta-adrenomimetic in the blood the authors proposed the biological testing of the serum and plasma on the isolated myometrium of the rat. For this purpose obsidan was used as a beta-adrenoblocker. It was shown that endogenous beta-adrenomimetic different from adrenaline was present in the blood of males, nonpregnant and pregnant females and parturients. Besides, its concentration increased in pregnancy and remained high early in labor.
摘要
为了揭示血液中的内源性β-肾上腺素能物质，作者提出对大鼠离体子宫肌层进行血清和血浆的生物学检测。为此，使用氧烯洛尔作为β-肾上腺素能阻滞剂。结果表明，雄性、未孕和孕龄雌性以及产妇的血液中存在不同于肾上腺素的内源性β-肾上腺素能物质。此外，其浓度在怀孕期间升高，并在分娩早期保持在较高水平。
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