Shpilberg Katya A, Esses Steven J, Fowkes Mary E, Chari Ajai, Sacher Michael, Naidich Thomas P
Department of Radiology, Icahn School of Medicine, Mount Sinai Health System, New York.
Department of Radiology, Icahn School of Medicine, Mount Sinai Health System, New York.
Clin Imaging. 2015 Mar-Apr;39(2):213-9. doi: 10.1016/j.clinimag.2014.11.017. Epub 2014 Nov 26.
Involvement of the central nervous system by multiple myeloma is rare and has a very poor prognosis. Magnetic resonance imaging of the head and spine plays an important role in diagnosing central nervous system involvement with multiple myeloma. We retrospectively analyzed the imaging features of pathology-proven extraosseous intracranial and intraspinal multiple myeloma from 2002 to 2013. The most common imaging manifestations were extraaxial nonosseous spinal lesions, cranial nerve involvement, and intracranial extraaxial nonosseous lesions. Different sites in the central nervous system may be affected by multiple myeloma, often simultaneously, producing a variety of imaging appearances.
多发性骨髓瘤累及中枢神经系统较为罕见，预后很差。头颅和脊柱的磁共振成像在诊断多发性骨髓瘤累及中枢神经系统方面发挥着重要作用。我们回顾性分析了2002年至2013年经病理证实的骨外颅内和脊柱内多发性骨髓瘤的影像学特征。最常见的影像学表现为椎管外非骨性脊柱病变、脑神经受累及颅内椎管外非骨性病变。中枢神经系统的不同部位可能同时受到多发性骨髓瘤的影响，产生多种影像学表现。
