Albanese G, Giorgetti P, Santagostino L, Crippa D, Sala G
Department of Dermatology, S. Gerardo Hospital, Monza, Italy.
Arch Dermatol. 1989 Nov;125(11):1540-2.
The chemotherapy of leishmaniasis is still far from satisfactory. Itraconazole, one of the most recent azole antifungal agents, appears to be well tolerated in man. Two patients with cutaneous leishmaniasis (Leishmania tropica), contracted in Saudi Arabia, were treated orally for 2 months with itraconazole (100 mg/d). Both recovered without side effects or abnormalities in their main biologic parameters.
利什曼病的化疗效果仍远不尽人意。伊曲康唑是最新的唑类抗真菌药物之一，在人体中似乎耐受性良好。两名在沙特阿拉伯感染热带利什曼原虫引起皮肤利什曼病的患者口服伊曲康唑（100毫克/天）治疗2个月。两人均康复，且主要生物学指标无副作用或异常。
