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脾脏炎性假瘤合并脾结核

Inflammatory pseudotumour of the spleen associated with splenic tuberculosis.

作者信息

Prieto-Nieto Maria Isabel, Pérez-Robledo Juan Pedro, Díaz-San Andrés Beatriz, Nistal Manuel, Rodríguez-Montes José Antonio

机构信息

Maria Isabel Prieto-Nieto, Juan Pedro Pérez-Robledo, Beatriz Díaz-San Andrés, José Antonio Rodríguez-Montes, Department of General and Digestive Surgery, La Paz University Hospital, Paseo de la Castellana, 28046 Madrid, Spain.

出版信息

World J Gastrointest Surg. 2014 Dec 27;6(12):248-52. doi: 10.4240/wjgs.v6.i12.248.

Abstract

Inflammatory pseudotumor (IPT) of the spleen is an uncommon entity with an uncertain aetiology. Inflammatory pseudotumors present diagnostic difficulties because the clinical and radiological findings tend to suggest a malignancy. The symptoms include weight loss, fever, and abdominal pain. Most cases of splenic IPT present solitary relatively large well circumscribed masses on imaging. The diagnosis in the majority of the cases is made after histopathologic study of splenectomy specimens. The IPTs that occur in the spleen and liver are typically associated with Epstein-Barr virus. Thirty-seven percent of all new cases of active tuberculosis infection are extrapulmonary tuberculosis and tuberculous lymphadenitis the most commonly occurring form of extrapulmonary tuberculosis. We report the case of an inflammatory pseudotumor of the spleen associated with splenic tuberculous lymphadenitis in a 50-year-old female patient who was preoperatively diagnosed with a malignant spleen tumour based on her history of breast of carcinoma.

摘要

脾脏炎性假瘤(IPT)是一种病因不明的罕见疾病。炎性假瘤的诊断存在困难,因为临床和影像学表现往往提示为恶性肿瘤。症状包括体重减轻、发热和腹痛。大多数脾脏IPT病例在影像学上表现为孤立的、相对较大的边界清晰的肿块。大多数病例的诊断是在对脾切除标本进行组织病理学研究后做出的。发生在脾脏和肝脏的IPT通常与EB病毒有关。所有活动性结核感染新病例中,37%为肺外结核,其中结核性淋巴结炎是最常见的肺外结核形式。我们报告一例50岁女性患者,其脾脏炎性假瘤合并脾结核性淋巴结炎,该患者因乳腺癌病史术前被诊断为脾脏恶性肿瘤。

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