Kabbara Bilal, Gauche Clement, Calmels Marie-Noelle, Lepage Benoit, Escude Bernard, Deguine Olivier, Fraysse Bernard, Marx Mathieu
*Department of Otology-Neurotology and Skull Base Surgery, Purpan University Hospital, Toulouse, France; †Department of Statistics, Paul Sabatier University, Toulouse, France; ‡Department of Neuroradiology, Clinique Pasteur, Toulouse, France; and §Centre National de la Recherche Scientifique (CNRS), CerCo, Toulouse, France.
Otol Neurotol. 2015 Mar;36(3):e73-8. doi: 10.1097/MAO.0000000000000692.
To describe the hearing outcomes in patients with far-advanced otosclerosis and to identify the best initial approach based on preoperative word recognition scores (WRS), pure tone averages (PTA), and radiological classification.
Retrospective case review.
Academic neurotology tertiary referral center.
All patients (n = 58) with preoperative air conduction PTA less than 85 dB (HL), disyllabic WRS less than or equal to 50% at 60 dB (HL) with well-fitted hearing aids, and evidence of otosclerosis on CT scan, treated in our department over the past 20 years.
Stapedotomy, cochlear implantation, or both.
Postoperative WRS after a minimum of 12 months' follow-up, percentage of patients with WRS greater than 50%. Reliability of air and bone conduction PTAs and WRS in predicting failure of stapedotomy.
Fifty-eight patients were divided into three groups: group I, primary stapedotomy (n = 32); group II, primary cochlear implantation (n = 9); and group III, secondary cochlear implantation (with a previous history of stapedotomy) (n = 25). The mean postoperative WRS were 50.6% (± 34), 75% (± 17), and 72% (± 20), respectively. Sixty percent of patients in the stapedotomy group had a postoperative WRS greater than 50% requiring no further treatment, compared to 85% for cochlear implant recipients. No specific predictive factors for stapedotomy outcome could be identified. Surgical difficulties during cochlear implantation were significantly higher in patients with advanced radiological stage.
Although cochlear implantation gives better overall results, stapedotomy with hearing aids can still be very effective in the management of patients with far-advanced otosclerosis. It should therefore be proposed as a first-line treatment.
描述极重度耳硬化症患者的听力结果,并根据术前言语识别得分(WRS)、纯音平均听阈(PTA)和放射学分类确定最佳初始治疗方法。
回顾性病例分析。
学术性耳神经学三级转诊中心。
过去20年在我科接受治疗的所有患者(n = 58),这些患者术前气导PTA低于85 dB(HL),佩戴合适助听器时在60 dB(HL)下双音节WRS小于或等于50%,且CT扫描有耳硬化症证据。
镫骨手术、人工耳蜗植入或两者皆用。
至少随访12个月后的术后WRS,WRS大于50%的患者百分比。气导和骨导PTA以及WRS预测镫骨手术失败的可靠性。
58例患者分为三组:第一组,初次镫骨手术(n = 32);第二组,初次人工耳蜗植入(n = 9);第三组,二次人工耳蜗植入(有镫骨手术史)(n = 25)。术后平均WRS分别为50.6%(± 34)、75%(± 17)和72%(± 20)。镫骨手术组60%的患者术后WRS大于50%,无需进一步治疗,而人工耳蜗植入患者为85%。未发现镫骨手术结果的特定预测因素。放射学分期较晚的患者人工耳蜗植入手术难度明显更高。
虽然人工耳蜗植入总体效果更好,但佩戴助听器的镫骨手术在极重度耳硬化症患者的治疗中仍可能非常有效。因此,应将其作为一线治疗方法。