Abela Stefan, Cameron Malcolm, Bister Dirk
Department or Oral Health, Norfolk and Norwich University Hospital NHS Foundation Trust, United Kingdom.
Aust Orthod J. 2014 Nov;30(2):214-20.
Cherubism is a rare hereditary disease that frequently manifests as a painless enlargement of the mandible and/or maxilla. The disease usually progresses rapidly during the first and second decades of life but it is self-limiting and often regresses. Although few orthodontic case reports describing cherubic patients exist, the timing and extent of surgical intervention is controversial.
This present paper aims to review the treatment literature and provide a case report of a patient who underwent orthodontic/surgical management.
The patient presented with severe cherubism in her late teenage years; her main complaint was poor facial and dental appearance. Multiple teeth were missing and those present demonstrated significant preoperative root resorption. Treatment consisted of orthodontic alignment of the upper anterior teeth and a recontouring osteotomy.
Confirmed by the patient, the combination approach led to a significant improvement in facial aesthetics and better self-esteem. Tooth movement through the osseous lesions was uneventful and no further root resoption was observed.
Orthodontic treatment may be undertaken in those affected by Cherubism even with pre-existing idiopathic root resorption, but patients need to be appropriately informed and consented.
cherubism是一种罕见的遗传性疾病，常表现为下颌骨和/或上颌骨无痛性肿大。该疾病通常在生命的第一个和第二个十年中迅速发展，但具有自限性，且常自行消退。尽管描述cherubic患者的正畸病例报告很少，但手术干预的时机和范围仍存在争议。
本文旨在回顾治疗文献，并提供一例接受正畸/外科治疗患者的病例报告。
该患者在青少年后期出现严重的cherubism；她的主要诉求是面部和牙齿外观不佳。多颗牙齿缺失，现存牙齿术前出现明显的牙根吸收。治疗包括上前牙的正畸排齐和轮廓重塑截骨术。
经患者确认，联合治疗方法显著改善了面部美观，增强了自尊心。牙齿通过骨病变移动顺利，未观察到进一步的牙根吸收。
即使存在特发性牙根吸收，受cherubism影响的患者也可进行正畸治疗，但需要对患者进行适当的告知并取得同意。
