Muir Brad, Brown Courtney, Brown Tara, Tatlow Dionne, Buhay Jeremy
Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Canada. ; Associate Professor, Faculty of Clinical Education, Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Canada.
Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Canada. ; Sports Sciences Resident, Department of Graduate Studies, Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Canada.
J Can Chiropr Assoc. 2014 Dec;58(4):467-80.
The purpose of this pilot study was to determine the scientific and process feasibility in an effort to direct future larger trials.
Scientific Feasibility: Twelve subjects were randomly allocated to an intervention and a control group. The intervention protocol consisted of intraoral vibration therapy on the muscles of mastication bilaterally for a period of 1 minute per muscle. Process Feasibility: Several feasibility outcomes were examined including recruitment and retention rates and consent.
Scientific Feasibility: Large effect sizes were generated for both mouth opening and VAS in favour of the intervention group. Process Feasibility: a recruitment ratio of 2.3 respondents to 1 participant was determined, along with a retention to loss ratio of 13:1 and a consent to loss ratio of 12:0.
Scientific Feasibility: The scientific results should be interpreted with caution due to the small sample sizes employed. The study seems to support the scientific feasibility of a future larger single treatment trial. Process Feasibility: Recruitment and retention rates and ratios seem to support future studies. Utilizing the feasibility results of the current study to direct a future larger multiple treatment trial consistent with other comparable TMD studies however is limited.
本初步研究的目的是确定科学和过程可行性,以便指导未来更大规模的试验。
科学可行性:12名受试者被随机分配到干预组和对照组。干预方案包括对双侧咀嚼肌进行口腔内振动治疗,每块肌肉治疗1分钟。过程可行性:检查了几个可行性结果,包括招募率、留存率和同意率。
科学可行性:张口度和视觉模拟评分(VAS)均产生了较大的效应量,支持干预组。过程可行性:确定的招募比例为2.3名受访者对应1名参与者,留存与流失比例为13:1,同意与流失比例为12:0。
科学可行性:由于样本量较小,科学结果应谨慎解释。该研究似乎支持未来更大规模单一治疗试验的科学可行性。过程可行性:招募率、留存率和比例似乎支持未来的研究。然而,利用本研究的可行性结果来指导未来与其他类似颞下颌关节紊乱病(TMD)研究一致的更大规模多治疗试验是有限的。