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双胎贫血-红细胞增多序列征:三例报告

Twin anemia polycythemia sequence: a report of three cases.

作者信息

Casanova Joao, Paiva Catarina, Carvalho Carmen, Cunha Ana C

机构信息

Department of Obstetrics and Gynecology, Porto Hospital Center, Poro, Portugal.

出版信息

J Reprod Med. 2014 Nov-Dec;59(11-12):596-8.

PMID:25552134
Abstract

BACKGROUND

Vascular anastomoses in monochorionic placentas are the key factor in the develop- ment of several complications, including twin anemiapolycythemia sequence (TAPS). TAPS is an uncommon form of chronic fetofetal transfusion, characterized by large intertwin hemoglobin (Hb) differences in the absence of amniotic fluid discordances.

CASE

We report 3 unusual cases of spontaneous TAPS. Looking to the intertwin Hb differences, each case fits in a different stage of postnatal twin anemia-polycythemia classification. Five of the 6 twins had a good outcome despite major hemodynamic changes.

CONCLUSION

Spontaneous TAPS is by far more infrequent than its postlaser counterpart. Our report is somewhat uncommon due to the fact that the 3 cases were spontaneous, consecutive, and each one fit as an example of the various degrees of severity according to the described classifications of this condition.

摘要

背景

单绒毛膜胎盘的血管吻合是包括双胎贫血-红细胞增多序列征(TAPS)在内的几种并发症发生发展的关键因素。TAPS是一种罕见的慢性胎儿-胎儿输血形式,其特征是双胎间血红蛋白(Hb)差异较大,而羊水无差异。

病例

我们报告3例自发性TAPS的罕见病例。根据双胎间Hb差异,每个病例符合出生后双胎贫血-红细胞增多分类的不同阶段。6例双胞胎中有5例尽管有重大血流动力学变化,但结局良好。

结论

自发性TAPS远比激光治疗后的TAPS少见。我们的报告有些罕见,因为这3例病例是自发的、连续的,并且根据这种情况的描述分类,每一例都符合不同严重程度的例子。

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