A hippo "AKT" regulates cardiomyocyte proliferation.
作者信息
Xiao Feng, Kimura Wataru, Sadek Hesham A
机构信息
From the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
出版信息
Circ Res. 2015 Jan 2;116(1):3-5. doi: 10.1161/CIRCRESAHA.114.305325.
Abstract
摘要
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本文引用的文献
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2
Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model.
Circ Res. 2014 Jul 18;115(3):354-63. doi: 10.1161/CIRCRESAHA.115.303632. Epub 2014 May 15.
3
The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032.
4
Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus.
Nature. 2014 Apr 24;508(7497):541-5. doi: 10.1038/nature13079. Epub 2014 Mar 9.
5
Hippo signaling impedes adult heart regeneration.
Development. 2013 Dec;140(23):4683-90. doi: 10.1242/dev.102798.
6
Hippo pathway effector Yap promotes cardiac regeneration.
Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110. Epub 2013 Aug 5.
7
Meis1 regulates postnatal cardiomyocyte cell cycle arrest.
Nature. 2013 May 9;497(7448):249-253. doi: 10.1038/nature12054. Epub 2013 Apr 17.
8
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts.
Circ Res. 2013 Jun 7;112(12):1557-66. doi: 10.1161/CIRCRESAHA.112.300658. Epub 2013 Apr 10.
9
The YAP and TAZ transcription co-activators: key downstream effectors of the mammalian Hippo pathway.
Semin Cell Dev Biol. 2012 Sep;23(7):785-93. doi: 10.1016/j.semcdb.2012.05.004. Epub 2012 May 29.
10
YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy.
Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2394-9. doi: 10.1073/pnas.1116136109. Epub 2012 Jan 30.
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